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Investigación
IRAS – Infecciones Relacionadas con la Asistencia Sanitaria y Resistencias frente a Antimicrobianos
Líneas de investigación
Contenidos con Investigacion .
IRAS – Infecciones Relacionadas con la Asistencia Sanitaria y Resistencias frente a Antimicrobianos
- Investigación en la epidemiología de las Infecciones Relacionadas con la Asistencia Sanitaria (IRAS). Valorar la calidad asistencial en cirugías frecuentemente realizadas en España usando como indicador la incidencia de IRAS.
- Variación geográfica de la carga de enfermedad por IRAS en hospitales.
- Estimación del impacto de la organización hospitalaria en la incidencia de IRAS.
- Investigación en la epidemiología de las Resistencias a Antimicrobianos (RAM).
- Valoración de la idoneidad de los tratamientos antimicrobianos en pacientes mayores con patologías crónicas de base.
- Estimación de costes asociados al manejo de las infecciones de microrganismos resistentes.
- Generación de modelos de predicción de riesgo de infección y de riesgo de infección por microorganismo resistentes.
- El “convenio entre el Instituto de Salud Carlos III O.A., M.P. y Clínica Barceloneta S.A. para el desarrollo de actividades relacionadas con el estudio del impacto de los antimicrobianos en la incidencia de resistencias en pacientes mayores atendidos en hospitales de atención intermedia de Barcelona”. Número de expediente: RCN-CNU202400125 Vigente hasta el 04/10/2028
- El proyecto coordinado “Desarrollo de Infraestructuras ISCIII para la creación, estandarización y producción de fagos útiles en Infecciones bacterianas pulmonares crónicas. (DISCIII-Phage)” Número de expediente: COOP24CIII/00010. Vigente hasta el 30 de Junio de 2028. Programa COOPERA-ISCIII para la realización de proyectos coordinados estratégicos transversales en el marco de la AES intramural (AESI) 2024.
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Publicaciones destacadas
Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study.
Galán I, Fontán J, Ortiz C, López-Cuadrado T, Téllez-Plaza M, García-Esquinas E. Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study. Addict Behav. 2024 Nov;158:108108.
PUBMED DOIA growing disconnection from nature. Urgent call to action for a nature prescription global health alliance.
Ortega-García JA, Martínez-Gómez C, Bach A, Benitez-Rodríguez L, Ramis R; en representación de la Alianza GRSIA. A growing disconnection from nature. Urgent call to action for a nature prescription global health alliance. An Pediatr (Engl Ed). 2024 Jun;100(6):e10-e12.
PUBMED DOIMeasles Among the Foreign-Born Population Residing in Spain, 2014–2022: Missed Opportunities for Vaccination.
Noemí López-Perea, Teresa López-Cuadrado, Aurora Fernández-García, Juan E. Echevarría, Josefa Masa-Calles. Vaccines, 2024
DOIAssociation Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic.
Agurto-Ramírez A, Pino-Rosón C, Ayala A, Falcón M, Rodríguez-Blázquez C, Forjaz MJ, Romay-Barja M. Association Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic. Int J Public Health. 2023 Sep 26;68:1606049.
PUBMED DOIRecent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study
López-Cuadrado T, Susser E, Martínez-Alés G. Recent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study. Bipolar Disord. 2024 Dec;26(8):801-809.
PUBMED DOIApproximate Bayesian inference for multivariate point pattern analysis in disease mapping
Palmí-Perales F, Gómez-Rubio V, López-Abente G, Ramis R, Sanz-Anquela JM, Fernández-Navarro P. Approximate Bayesian inference for multivariate point pattern analysis in disease mapping. Biom J. 2021 Mar;63(3):632-649.
PUBMED DOIConsumption patterns and key motivational drivers: an analysis of food behavior in Spanish households
Beltrán-de-Miguel B, Del-Pozo-de-la-Calle S, Cuadrado-Vives C, Ruiz-Moreno E. Consumption patterns and key motivational drivers: an analysis of food behavior in Spanish households. Front Nutr. 2025 Jun 23;12:1526957.
PUBMED DOIExposure to green spaces, cardiovascular risk biomarkers and incident cardiovascular disease in older adults: The Seniors-Enrica II cohort
Scheer C, Plans-Beriso E, Pastor-Barriuso R, Ortolá R, Sotos-Prieto M, Cabañas-Sánchez V, Gullón P, Ojeda Sánchez C, Ramis R, Fernández-Navarro P, Rodríguez-Artalejo F, García-Esquinas E. Exposure to green spaces, cardiovascular risk biomarkers and incident cardiovascular disease in older adults: The Seniors-Enrica II cohort. Environ Int. 2024 Mar;185:108570.
PUBMED DOIMammographic density in the environs of multiple industrial sources.
Jiménez T, Pollán M, Domínguez-Castillo A, Lucas P, Sierra MÁ, Castelló A, Fernández de Larrea-Baz N, Lora-Pablos D, Salas-Trejo D, Llobet R, Martínez I, Pino MN, Martínez-Cortés M, Pérez-Gómez B, Lope V, García-Pérez J. Mammographic density in the environs of multiple industrial sources. Sci Total Environ. 2023 Jun 10;876:162768.
PUBMED DOIQuality, acceptability and usability of self-sampling kits used by non-healthcare professionals for STI diagnosis in Spain: a single-blind study.
Gómez-Castellá J, Cobos Briz M, Nuño N, Diaz A, Bru-Gorraiz FJ, Martín-Gorgojo A, Almonacid-Garrido MC, Mir A, Muñoz M, del Amo J. et al. Sex Transm Infec. 2024. 0:1–6. doi:10.1136/sextrans-2024-056124.
PUBMEDIncreasing trends in hepatitis E hospitalisations in Spain, 1997 to 2019. Euro Surveill. 2024;29(43):pii=2400118.
Guerrero-Vadillo María, Peñuelas Marina, Carmona Rocío, León-Gómez Inmaculada, Varela Carmen.
DOIHealth-related quality of life in people with HIV from the multicentre CoRIS cohort in Spain: Associated factors and short-term changes over time.
Izquierdo R, Suárez-García I, Marco-Sánchez C, Pérez-Latorre L, Riera M, Cano J, Viladés C, Reus S, Olalla J, González-Ruano P, Orviz E, Díaz A, Moreno S, Jarrín I; CoRIS cohort. HIV Med. 2025 Jan 21.
PUBMED DOIEffectiveness of XBB.1.5 Monovalent COVID-19 Vaccines During a Period of XBB.1.5 Dominance in EU/EEA Countries, October to November 2023: A VEBIS-EHR Network Study.
Monge S, Humphreys J, Nicolay N, Braeye T, Van Evercooren I, Holm Hansen C, et al. Influenza Other Respir Viruses. 2024 Apr;18(4):e13292.
PUBMED DOIDevelopment and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children.
Pons R, Pearson TS, Perez-Dueñas B, Garcia-Cazorla A, Kurian MA, Dalivigka Z, Zouvelou V, Outsika C, Kokkinou E, Sigatullina-Bondarenko M, Darling A, O'Callaghan MDM, Spaull R, Steel DBD, Salamou E, Forjaz MJ, Rodriguez-Blazquez C. Development and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children. Mov Disord. 2025 Aug;40(8):1669-1679.
PUBMED DOITraffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.
Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero JC, Ramis R. Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study. Antioxidants (Basel). 2023 Dec 15;12(12):2122.
PUBMED DOIDifferential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults.
Rodriguez-Hernandez Z, Bel-Aguilar J, Moreno-Franco B, Grau-Perez M, Redon J, Gomez-Ariza JL, Garcia-Barrera T, Olmedo P, Gil F, Cenarro A, Civeira F, Puzo J, Casasnovas JA, Banegas JR, Sotos-Prieto M, Ortola R, Laclaustra M, Rodriguez-Artalejo F, Garcia-Esquinas E, Tellez-Plaza M, Pastor-Barriuso R. Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults. Nutr Diabetes. 2025 Feb 13;15(1):5.
PUBMED DOIReduced pertussis disease severity in infants following the introduction of pertussis vaccination of pregnant women in Spain, 2015-2019.
Parisi A, Nuñez O, López-Perea N, Masa-Calles J. Vaccine. 2024 Mar 25:S0264-410X(24)00315-3.
DOIRisk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.
Ayuso-Álvarez A, Blasco Hernández T, Benito Llanes A. Percepción del riesgo de los profesionales sanitarios ante el primer caso de infección secundaria por ébola en España [Risk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.]. Rev Esp Salud Publica. 2021 Sep 7;95:e202109136.
PUBMEDHospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study
Vázquez-Giraldo P, Muñoz-Sanjosé A, López-Cuadrado T. Hospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study. Int J Eat Disord. 2024 Nov;57(11):2299-2305.
PUBMED DOIDifferent spatial pattern of municipal prostate cancer mortality in younger men in Spain
Rodriguez-Sanchez L, Fernández-Navarro P, López-Abente G, Nuñez O, Fernández de Larrea-Baz N, Jimenez-Moleón JJ, Páez Borda Á, Pollán M, Perez-Gomez B. Different spatial pattern of municipal prostate cancer mortality in younger men in Spain. PLoS One. 2019 Jan 25;14(1):e0210980.
PUBMED DOIDeterminants of Adherence to World Cancer Research Fund/American Institute for Cancer Research Recommendations in Women with Breast Cancer
Pachón Olmos V, Pollán M, Fernández de Larrea-Baz N, Fernández-Morata J, Ruiz-Moreno E, García-Pérez J, Castelló A, Sierra MÁ, Lucas P, Alonso-Ledesma I, Stradella A, Cantos B, Ramón Y Cajal T, Santisteban M, Seguí MÁ, Santaballa Bertrán A, Granja M, Camps-Herrero J, Recalde S, Mendez M, Calvo Verges N, Pérez-Gómez B, Pastor-Barriuso R, Lope V. Determinants of Adherence to World Cancer Research Fund/American Institute for Cancer Research Recommendations in Women with Breast Cancer. Cancers (Basel). 2025 Feb 19;17(4):708.
PUBMED DOISelenium and impaired physical function in US and Spanish older adults
García-Esquinas E, Carrasco-Rios M, Ortolá R, Sotos Prieto M, Pérez-Gómez B, Gutiérrez-González E, Banegas JR, Queipo R, Olmedo P, Gil F, Tellez-Plaza M, Navas-Acien A, Pastor-Barriuso R, Rodríguez-Artalejo F. Selenium and impaired physical function in US and Spanish older adults. Redox Biol. 2021 Jan;38:101819.
PUBMED DOIResidential proximity to industrial pollution and mammographic density.
Jiménez T, Pollán M, Domínguez-Castillo A, Lucas P, Sierra MÁ, Castelló A, Fernández de Larrea-Baz N, Lora-Pablos D, Salas-Trejo D, Llobet R, Martínez I, Pino MN, Martínez-Cortés M, Pérez-Gómez B, Lope V, García-Pérez J. Mammographic density in the environs of multiple industrial sources. Sci Total Environ. 2023 Jun 10;876:162768.
PUBMED DOISharp increase in gonorrhoea notifications among young people, EU/EEA, July 2022 to June 2023.
Nerlander L, Champezou L, Gomes Dias J, Aspelund G, Berlot L, Constantinou E, Díaz A, Epštein J, Fogarassy E, Hernando V, Hoffmann P, Igoe D, Klavs I, Pinto Leite P, Liitsola K, McIntyre A, Molnár Z, Olsen Anne O, Pires-Afonso Y, Putniņa R, Rudaitis K, Siakallis G, de Stoppelaar S, Suligoi B, Hannila-Handelberg T, Velicko I, Cabral Veríssimo V, Visser M, Wessman M, Mårdh O. Euro Surveill. 2024; 29(10):pii=2400113.
PUBMED DOITrends in new HIV diagnoses and factors contributing to late diagnosis among migrant populations in EU/EEA countries, 2014 to 2023.
Reyes-Urueña J, Stoppa G, Pizzolato F, van der Werf MJ, Deogan C, Cabral-Veríssimo V, Cortes-Martins H, Deblonde J, Diaz A, Hernando V, Milunka-Kojic E, Mossong J, O’Donnell K, Op de Coul E, Tsiara C, van Leest L, Van Beckhoven D, Wessman M, Whittaker R, the EU/EEA HIV network. Euro Surveill. 2024; 29(48): pii=2400759.
PUBMED DOICaracterísticas epidemiológicas de los brotes de hepatitis A en España (años 2015-2019)
Guerrero-Vadillo M, Peñuelas Martínez M, Varela Martínez C. Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019). BES [Internet]. 24 de enero de 2022 ;29(2). Disponible en: //revista.isciii.es/index.php/bes/article/view/1124
Markers of inflammation and immune dysfunction and non-AIDS cancer risk in adults with HIV. v
Izquierdo R, Vallejo A, Suárez-García I, Martín-Hondarza A, Gutierrez F, Perez-Molina JA, García DV, Macías J, Rivero A, Olalla J, Montero-Alonso M, Asensi V, Moreno S, Jarrín I, Rava M; CoRIS cohort. J Acquir Immune Defic Syndr. 2025 Apr 7.
PUBMED DOICOVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA.1/BA.2 lineages among adults and adolescents in a multicentre primary care study, Europe, December 2021 to June 2022.
Lanièce Delaunay C, Martínez-Baz I, Sève N, Domegan L, Mazagatos C, Buda S, et al. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2024 Mar;29(13).
PUBMED DOIVaccination trends in people with HIV infection participanting in the hospital-based survey of patients infected with HIV, 2006-2021.
Hernando V, Suárez L, Gutiérrez G, López JC, Navarrro-Soler R, Cabello A, Sanz J, Suarez-García I, Fernández MT, Losa JE, Pérez JL, Ramos-Ruperto L, Pérez-Elias MJ, Ben Cheikh El Aayuni W, Cuesta M, Gonzalez G, Izquierdo A, Viloria L, López I, Martínez E, Castrillejo D, Jaume Armengual MG, Belmonte MA, Arraiza A, de la Torre J, Miqueleiz E, Marcos H, Ruiz-Algueró M, Villegas T, Simón L, Diaz A, por el Grupo de Trabajo de la Encuesta Hospitalaria. Enferm Infecc Microbiol Clin (Engl Ed). 2024 Aug-Sep;42(7):339-346.
PUBMED DOIValidation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q).
Weintraub D, Chaudhuri KR, Schrag A, Martinez-Martin P, Rizos A, Mamikonyan E, Gallagher J, Schoen I, Staunton J, Fernandes MP, Rodriguez-Blazquez C. Validation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q). Mov Disord. 2025 Jun;40(6):1037-1046.
PUBMED DOIExploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence.
Ojeda Sánchez C, García-Pérez J, Gómez-Barroso D, Domínguez-Castillo A, Pardo Romaguera E, Cañete A, Ortega-García JA, Ramis R. Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence. Int J Environ Res Public Health. 2023 Jan 31;20(3):2506.
PUBMED DOIMulticohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach
Domingo-Relloso A, Riffo-Campos AL, Zhao N, Ayala G, Haack K, Manterola C, Rhoades DA, Umans JG, Fallin MD, Herreros-Martinez M, Pollan M, Boerwinkle E, Platz EA, Jones MR, Bressler J, Joehanes R, Ryan CP, Gonzalez JR, Levy D, Belsky DW, Cole SA, Michaud DS, Navas-Acien A, Tellez-Plaza M. Multicohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach. JACC CardioOncol. 2024 Sep 10;6(5):731-742.
PUBMED DOICoordinated public health actions following the identification of a measles case arriving on an international flight, Spain: December 2022-January 2023.
López-Perea N et al. Travel Med Infect Dis, 2024.
DOIHow patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study.
Romay-Barja M, Pascual-Carrasco M, De Tena-Dávila MJ, Falcón M, Rodriguez-Blazquez C, Forjaz MJ, Ayala A, Molina-de la Fuente I, Burgos A, Muñoz A, Benito A. How patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study. BMJ Open. 2021 May 20;11(5):e048702.
PUBMED DOIImpact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders.
López-Cuadrado T, Ortiz C, Ayuso-Álvarez A, Galán I. Impact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders. J Psychiatr Res. 2024 Jan;169:292-297.
PUBMED DOITrends in mortality from cutaneous malignant melanoma in Spain (1982-2016): sex-specific age-cohort-period effects
Gutiérrez-González E, López-Abente G, Aragonés N, Pollán M, Pastor-Barriuso R, Sánchez MJ, Pérez-Gómez B. Trends in mortality from cutaneous malignant melanoma in Spain (1982-2016): sex-specific age-cohort-period effects. J Eur Acad Dermatol Venereol. 2019 Aug;33(8):1522-1528.
PUBMED DOIIntake of fruit, vegetables and pulses, and all-cause, cardiovascular and cancer mortality: Results from a population-based prospective study
Martínez-Castañeiras P, Ortiz C, Fernandez de Larrea-Baz N, Lope V, Sánchez-Gordón G, Ruiz-Moreno E, Alonso I, Garcia-Esquinas E, Pérez-Gómez B, Pastor-Barriuso R, Galán I, Castelló A. Intake of fruit, vegetables and pulses, and all-cause, cardiovascular and cancer mortality: Results from a population-based prospective study. Public Health. 2025 Feb;239:169-178.
PUBMED DOICausal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults
García-Esquinas E, Ortolá R, Martínez-Gómez D, Damián J, Prina M, Rodríguez-Artalejo F, Pastor-Barriuso R. Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults. Int J Epidemiol. 2021 Jul 9;50(3):852-865.
PUBMED DOI