Protegemos tu salud a través de la Ciencia
Investigación
IRAS – Infecciones Relacionadas con la Asistencia Sanitaria y Resistencias frente a Antimicrobianos
Líneas de investigación
Contenidos con Investigacion .
IRAS – Infecciones Relacionadas con la Asistencia Sanitaria y Resistencias frente a Antimicrobianos
- Investigación en la epidemiología de las Infecciones Relacionadas con la Asistencia Sanitaria (IRAS). Valorar la calidad asistencial en cirugías frecuentemente realizadas en España usando como indicador la incidencia de IRAS.
- Variación geográfica de la carga de enfermedad por IRAS en hospitales.
- Estimación del impacto de la organización hospitalaria en la incidencia de IRAS.
- Investigación en la epidemiología de las Resistencias a Antimicrobianos (RAM).
- Valoración de la idoneidad de los tratamientos antimicrobianos en pacientes mayores con patologías crónicas de base.
- Estimación de costes asociados al manejo de las infecciones de microrganismos resistentes.
- Generación de modelos de predicción de riesgo de infección y de riesgo de infección por microorganismo resistentes.
- El “convenio entre el Instituto de Salud Carlos III O.A., M.P. y Clínica Barceloneta S.A. para el desarrollo de actividades relacionadas con el estudio del impacto de los antimicrobianos en la incidencia de resistencias en pacientes mayores atendidos en hospitales de atención intermedia de Barcelona”. Número de expediente: RCN-CNU202400125 Vigente hasta el 04/10/2028
- El proyecto coordinado “Desarrollo de Infraestructuras ISCIII para la creación, estandarización y producción de fagos útiles en Infecciones bacterianas pulmonares crónicas. (DISCIII-Phage)” Número de expediente: COOP24CIII/00010. Vigente hasta el 30 de Junio de 2028. Programa COOPERA-ISCIII para la realización de proyectos coordinados estratégicos transversales en el marco de la AES intramural (AESI) 2024.
|
|
|
Publicaciones destacadas
Risk of gastric cancer in the environs of industrial facilities in the MCC-Spain study.
García-Pérez J, Lope V, Fernández de Larrea-Baz N, Molina AJ, Tardón A, Alguacil J, Pérez-Gómez B, Moreno V, Guevara M, Castaño-Vinyals G, Jiménez-Moleón JJ, Gómez-Acebo I, Molina-Barceló A, Martín V, Kogevinas M, Pollán M, Aragonés N. Risk of gastric cancer in the environs of industrial facilities in the MCC-Spain study. Environ Pollut. 2021 Jun 1;278:116854.
PUBMED DOIEffectiveness of MVA-BN vaccination in a population at high-risk of mpox: a Spanish cohort study.
Fontán-Vela M, Hernando V, Olmedo C, Coma E, Martínez M, Moreno-Perez D, Lorusso N, Vázquez Torres M, Barbas Del Buey JF, Roig-Sena J, Pastor E, Galmés Truyols A, Artigues Serra F, Sancho Martínez RM, Latasa Zamalloa P, Pérez Martínez O, Vázquez Estepa A, García Rojas AJ, Barreno Estévez AI, Sánchez-Migallón Naranjo A, Pérez Martín JJ, Peces Jiménez P, Morales Romero R, Castilla J, García Cenoz M, Huerta Huerta M, Lieve Dirk Boone A, Macías Ortiz MJ, Álvarez Río V, Rodríguez Recio MJ, Merino Díaz M, Berradre Sáenz B, Villegas-Moreno MT, Limia A, Diaz A, Monge S; Spanish MPOX vaccine effectiveness study group. Clin Infect Dis. 2024; 78(2):476-483.
PUBMED DOIPrevalence of chronic HCV infection in EU/EEA countries in 2019 using multiparameter evidence synthesis.
Thomadakis C, Gountas I, Duffell E, Gountas K, Bluemel B, Seyler T, Pericoli FM, Kászoni-Rückerl I, El-Khatib Z, Busch M, Schmutterer I, Vanwolleghem T, Klamer S, Plettinckx E, Mortgat L, Van Beckhoven D, Varleva T, Lana Kosanovic Licina M, Nemeth Blazic T, Nonković D, Theophanous F, Nemecek V, Maly M, Brehm Christensen P, Cowan S, Rüütel K, Brummer-Korvenkontio H, Brouard C, Steffen G, Krings A, Dudareva S, Zimmermann R, Nikolopoulou G, Molnár Z, Kozma E, Gottfredsson M, Murphy N, Kondili LA, Tosti ME, Ciccaglione AR, Suligoi B, Nikiforova R, Putnina R, Jancoriene L, Seguin-Devaux C, Melillo T, Boyd A, van der Valk M, Op de Coul E, Whittaker R, Kløvstad H, Stępień M, Rosińska M, Valente C, Tato Marinho R, Popovici O, Avdičová M, Kerlik J, Klavs I, Maticic M, Diaz A, del Amo J, Lundberg Ederth J, Axelsson M, Nikolopoulos G. Lancet Reg Health Eur. 2023: 36:100792
PUBMED DOIBrotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020
Chong A, Peñuelas M, Guerrero M, Cabezas C, Díaz O, Martín C, et al. Brotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020. BES [Internet]. 29 de marzo de 2022;29(5):53-6. Disponible en: //revista.isciii.es/index.php/bes/article/view/1157
Effectiveness and tolerability of dolutegravir/lamivudine in virologically suppressed people with HIV at 96 weeks in a multicentre cohort.
Suárez-García I, Alejos B, Moreno C, de Miguel R, Aldámiz-Echevarría T, García-Fraile LJ, Tasias Pitarch M, Pérez Martinez D, Antela A, Moreno S, Jarrín I; CoRIS cohort. HIV Med. 2025 Dec 31.
PUBMED DOIRasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study.
Forjaz, M.J., Ayala, A., Schutte, L., Wissing MP, Temane QM, Campbell TCH, Carroll MTC. Rasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study. Soc Indic Res 179, 47–66 (2025).
DOICardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin.
Sagastume D, Siero I, Mertens E, Peñalvo JL. Cardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin. Curr Cardiol Rep. 2022 Dec;24(12):1799-1810.
PUBMED DOIInvestigating Local Patterns of Mumps Virus Circulation, Using a Combination of Molecular Tools
Gavilán AM, Perán-Ramos P, Sanz JC, García-Comas L, Pérez-Abeledo M, Castellanos AM, Berciano JM, López-Perea N, Masa-Calles J, Echevarría JE, Fernández-García A. Viruses. 2023 Dec 13;15(12):2420.
PUBMED DOIKey Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment.
Romay-Barja M, Iglesias-Rus L, Boquete T, Benito A, Blasco-Hernández T. Key Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment. Infect Dis Poverty. 2021 Apr 23;10(1):55.
PUBMED DOIClinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study
López-Cuadrado T, Szmulewicz A, Öngür D, Martínez-Alés G. Clinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study. Gen Hosp Psychiatry. 2023 Sep-Oct;84:234-240.
PUBMED DOISeverity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014
Severi E, Georgalis L, Pijnacker R, Veneti L, Turiac IA, Chiesa F, Rizzo C, Martinelli D, Vold L, Herrador BG, Martinez CV, Sanchez EVM, Semenza JC, Lopalco P, Dahlström LA, Giesecke J. Severity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014. International Journal of Infectious Diseases 2022; 118, 34-43
PUBMED DOIDiagnosis of HIV infection during pregnancy: Trends from a national cohort in Spain.
Suárez-García I, Alejos B, Moreno C, Izquierdo R, de la Cámara SP, Resa-Infante P, Merino VS, García-Arriaza J, Cabello-Úbeda A, Pérez-Martínez L, Palacios R, Hernando V, Jarrín I; CoRIS cohort. HIV Med. 2025 Nov 21.
PUBMED DOIVaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network.
Rose AMC, Pozo F, Martínez-Baz I, Mazagatos C, Bossuyt N, Cauchi JP, et al. Influenza Other Respir Viruses. 2024 Feb;18(2):e13255.
PUBMED DOISocial and behavioural determinants of syphilis: Modelling based on repeated cross-sectional surveys from 2010 and 2017 among 278,256 men who have sex with men in 31 European countries.
Mendez-Lopez A, Stuckler D, Marcus U, Hickson F, Noori T, Whittaker RN, Jansen K, Diaz A, Henszel L, Velter A, Semenza JC, Schmidt AJ. Lancet Reg Health Eur. 2022; 22:100483.
PUBMED DOIOmics feature selection with the extended SIS R package: identification of a body mass index epigenetic multimarker in the Strong Heart Study
Domingo-Relloso A, Feng Y, Rodriguez-Hernandez Z, Haack K, Cole SA, Navas-Acien A, Tellez-Plaza M, Bermudez JD. Omics feature selection with the extended SIS R package: identification of a body mass index epigenetic multimarker in the Strong Heart Study. Am J Epidemiol. 2024 Jul 8;193(7):1010-1018.
PUBMED DOIThe effectiveness of lifestyle interventions on type 2 diabetes and gestational diabetes incidence and cardiometabolic outcomes: A systematic review and meta-analysis of evidence from low- and middle-income countries.
Sagastume D, Siero I, Mertens E, Cottam J, Colizzi C, Peñalvo JL. The effectiveness of lifestyle interventions on type 2 diabetes and gestational diabetes incidence and cardiometabolic outcomes: A systematic review and meta-analysis of evidence from low- and middle-income countries. EClinicalMedicine. 2022 Sep 9;53:101650.
PUBMED DOIIdentification of methodological issues regarding direct impact indicators of COVID-19: a rapid scoping review on morbidity, severity and mortality.
Garriga C, Valero-Gaspar T, Rodriguez-Blazquez C, Diaz A, Bezzegh P, Daňková Š, Unim B, Palmieri L, Thiβen M, Pentz R, Cilović-Lagarija Š, Jogunčić A, Feteira-Santos R, Vuković J, Idavain J, Curta A, Sandu P, Vinko M, Forjaz MJ. Identification of methodological issues regarding direct impact indicators of COVID-19: a rapid scoping review on morbidity, severity and mortality. Eur J Public Health. 2024 Jul 1;34(Supplement_1):i3-i10.
PUBMED DOIUtility of MF-non coding region for measles molecular surveillance during post-elimination phase, Spain, 2017-2020.
Jacqueline C, Gavilán AM, López-Perea N, Penedos AR, Masa-Calles J, Echevarría JE, Fernández-García A; MMR Study Group. Front Microbiol. 2023 May 22;14:1143933.
DOIHepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022
Vidal A.R., Vaughan A., Innocenti F., Colombe S., Nerlander L., Rachwal N., Ciancio B.C., Mougkou A., Carvalho C., Delgado E., Mook P., De Muylder G., Peeters M., Tenev T., Golkocheva-Markova E., Jensen V.V.S., Koch A., Figoni J., Brouard C., Nikolopoulou G., Zisouli A., Murphy N., Broderick A., Goldberg L., Rich R., Sagie L.H., Tosti M.E., Suligoi B., Joosten R., Pijnacker R., Fjeldheim I., Heen E., Stȩpień M., Polański P., Marinho R.T., Martins J.V., Varela C., Avellón A., Andersson E., Mörk M.J., Mandal S., Watson C., Coughlan L., Chand M., Neill C., Bradley D.T., Li K., O'Leary M., McInnes N., Williams C.J., Moore C., Gjini A., Duffell E., Pebody R.. Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022. Euro Surveill. 2022;27(31):pii=2200483.
PUBMED DOILong-term effectiveness and tolerability of dolutegravir/lamivudine in treatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks.
Suárez-García I, Alejos B, Moreno C, Martín Torres J, Masiá M, García-Fraile LJ, Riera M, Dalmau D, Rodríguez-Rosado R, Muga R, Moreno S, Jarrín I; CoRIS cohort. J Antimicrob Chemother. 2025 Mar 3;80(3):682-691.
PUBMED DOIMonitoring progress towards elimination of hepatitis B and C in the EU/EEA.
Sharrock KC, Noori T, Axelsson M, Buti M, Diaz A, Fursa O, Hendrickx G, James C, Klavs I, Korenjak M, Maticic M, Mozalevskis A, Peters L, Rigoni R, Rosinska M, Ruutel K, Schatz E, Seyler T, Veldhuijzen I, Duffell E. PLOS Glob Public Health. 2022; 2(8): e0000841.
PUBMED DOIUrban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid.
Ojeda Sánchez C, Segú-Tell J, Gomez-Barroso D, Pardo Romaguera E, Ortega-García JA, Ramis R. Urban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid. Environ Res. 2021 Nov;202:111723.
PUBMED DOIVigilancia epidemiológica y virológica de la parotiditis en España, 2005-2022.
Horcas de Frutos A, López-Perea N, Fernández-García A, Gavilán AM, Echevarría JE, Olivares-Quintanar D, et al. BES [Internet]. 29 de septiembre de 2023, 31(3):139-65.
DOIInvestigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022
Larkin L., de la Gandara M.P., Hoban A., Pulford C., Silva N.J.-D., de Valk H., Browning L., Falkenhorst G., Simon S., Lachmann R., Dryselius R., Karamehmedovic N., Börjesson S., van Cauteren D., Laisnez V., Mattheus W., Pijnacker R., van den Beld M., Mossong J., Ragimbeau C., Vergison A., Brandal L.T., Lange H., Garvey P., Nielsen C.S., León S.H., Varela C., Chattaway M., Weill F.-X., Brown D., McKeown P. Investigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022. Euro Surveill2022;27(15):pii=2200314.
PUBMED DOIPregnancy in Women with HIV: Incidence and Outcomes over 19 Years in a Multi-Center Cohort in Spain.
Suárez-García I, Moreno C, Alejos B, Izquierdo R, Pérez de la Cámara S, Pardo OB, Arenzana CB, Pérez-Elías MJ, López TP, Imaz A, Curran A, Hernando V, Jarrín I; CoRIS cohort. AIDS Patient Care STDS. 2025 Oct;39(10):385-396.
PUBMED DOIAssociation of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: The national health and nutrition examination survey 1999-2018.
Gonzalez-Martin R, Grau-Perez M, Sebastian-Leon P, Diaz-Gimeno P, Vidal C, Tellez-Plaza M, Dominguez F. Association of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: The national health and nutrition examination survey 1999-2018. Environ Res. 2023 Sep 15;233:116514.
PUBMED DOIAn interregional measles outbreak in Spain with nosocomial transmission, November 2017 to July 2018.
Pampaka Despina, López-Perea Noemí, Fernández-García Aurora, Huertas-Zarco Isabel, Castellanos-Martínez Maite, Villatoro-Bongiorno Katja, Roig-Sena Javier, Torner Nuria, Mar Mosquera María, Echevarría Juan Emilio, Prats Joaquim Ferras, Masa-Calles Josefa. Euro Surveill. 2023;28(17):pii=2200634.
DOIVigilancia epidemiológica de Shigelosis en España, 2016-2021
Guerrero-Vadillo M, Peñuelas M, Herrera León S, Suarez Rodriguez B, Díaz A, Guzmán Herrador B, et al. Vigilancia epidemiológica de Shigelosis en España, 2016-2021. BES [Internet]. 21 de marzo de 2022;29(8):90-8. Disponible en: //revista.isciii.es/index.php/bes/article/view/1201
PUBMED DOITraffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.
Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero JC, Ramis R. Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study. Antioxidants (Basel). 2023 Dec 15;12(12):2122.
PUBMED DOIEpidemiology of Herpes Zoster in the pre-vaccination era: establishing the baseline for vaccination programme’s impact in Spain.
Risco Risco Carlos, Herrador Zaida, López-Parea Noemi, Martinez-Urbistondo Diego, del Villar Carrero Rafael Suarez, Masa-Calles Josefa.Euro Surveill. 2023;28(8):pii=2200390.
DOIPrimary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case control study.
Fernández de Larrea-Baz N, Pérez-Gómez B, Guerrero-Zotano Á, Casas AM, Bermejo B, Baena-Cañada JM, Antolin S, Sánchez-Rovira P, Ramos Vázquez M, Garcia-Sáenz JÁ, Antón A, Muñoz M, de Juan A, Jara C, Chacón JI, Arcusa A, Gil-Gil M, Adrover E, Oltra A, Brunet J, González S, Bezares S, Lope V, Martín M, Pollán M. Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study. Sci Rep. 2020 May 8;10(1):7741.
PUBMED DOISituación epidemiológica de la hepatitis A en España. Años 2021 y 2022
Guerrero-Vadillo M, Peñuelas M, Varela C. Situación epidemiológica de la hepatitis A en España. Años 2021 y 2022. BES [Internet]. 22 de diciembre de 2023;31(4):243-52.
DOIMeasles in Vaccinated People: Epidemiology and Challenges in Surveillance and Diagnosis in the Post-Elimination Phase. Spain, 2014–2020.
López-Perea, N.; Fernández-García, A.; Echevarría, J.E.; de Ory, F.; Pérez-Olmeda, M.; Masa-Calles, J. Viruses 2021, 13, 1982.
DOISituación epidemiológica prepandémica de la campilobacteriosis en España entre los años 2013-2019
Carbajo Otero A, Guerrero Vadillo M, León Gómez I, Varela Martínez MC. Situación epidemiológica prepandémica de la campilobacteriosis en España entre los años 2013-2019. Rev Salud ambient. 2023; 23(2):131-140.
DOILast cases of rubella and congenital rubella syndrome in Spain, 1997-2016: The succes of a vaccination program.
Elina Marjukka Seppälä, Noemí López-Perea, María de Viarce Torres de Mier, Juan E. Echevarría, Aurora Fernández-García, Josefa Masa-Calles. Vaccine, 2019,37.1, 169-175
DOI