Logo del Gobierno de España Logo del Ministerio de Ciencia e Innovación, lleva a la web del ministerio Logo del ISCIII, lleva a la página principal de este sitio web Logo del CNE

Protegemos tu salud a través de la Ciencia

Fondo del banner de laboratorios

Investigación

Líneas de investigación

Contenidos con Investigacion Subunidad de Bioinformática y Gestión de Datos .

Subunidad de Bioinformática y Gestión de Datos

Esta subunidad (Bioinformática y Gestión de Datos (BIOGEDA), Bioinformatics and Data Management (BIODAMA)), integrada en la Unidad de Epidemiología del Cáncer y Ambiental, tiene como principales líneas de investigación:

  • Diseño y desarrollo de instrumentos para la obtención de información y transmisión de la misma en la investigación epidemiológica.
  • Integración de fuentes de información y datos epidemiológicos
  • Bioinformática en el contexto de la epidemiología molecular/genética.
  • Infraestructuras de computación, almacenaje y transferencia de datos en salud.

Publicaciones destacadas

Categoría
Ordenar

Total Effective Xenoestrogen Burden in Serum Samples and Risk for Breast Cancer in a Population-Based Multicase-Control Study in Spain

Pastor-Barriuso R, Fernández MF, Castaño-Vinyals G, Whelan D, Pérez-Gómez B, Llorca J, Villanueva CM, Guevara M, Molina-Molina JM, Artacho-Cordón F, Barriuso-Lapresa L, Tusquets I, Dierssen-Sotos T, Aragonés N, Olea N, Kogevinas M, Pollán M. Total Effective Xenoestrogen Burden in Serum Samples and Risk for Breast Cancer in a Population-Based Multicase-Control Study in Spain. Environ Health Perspect. 2016 Oct;124(10):1575-1582. Epub 2016 May 20.

PUBMED

Pastor-Barriuso R, Ascunce N, Ederra M, Erdozáin N, Murillo A, Alés-Martínez JE, Pollán M. Recalibration of the Gail model for predicting invasive breast cancer risk in Spanish women: a population-based cohort study

Pastor-Barriuso R, Ascunce N, Ederra M, Erdozáin N, Murillo A, Alés-Martínez JE, Pollán M. Recalibration of the Gail model for predicting invasive breast cancer risk in Spanish women: a population-based cohort study. Breast Cancer Res Treat. 2013 Feb;138(1):249-59. doi: 10.1007/s10549-013-2428-y.

PUBMED

Air quality modeling and mortality impact of fine particles reduction policies in Spain

Boldo E, Linares C, Aragonés N, Lumbreras J, Borge R, de la Paz D, Pérez-Gómez B, Fernández-Navarro P, García-Pérez J, Pollán M, Ramis R, Moreno T, Karanasiou A, López-Abente G. Air quality modeling and mortality impact of fine particles reduction policies in Spain. Environ Res. 2014 Jan;128:15-26. doi: 10.1016/j.envres.2013.10.009. Epub 2013 Dec 22.

PUBMED

Childhood leukemia and residential proximity to industrial and urban sites

García-Pérez J, López-Abente G, Gómez-Barroso D, Morales-Piga A, Romaguera EP, Tamayo I, Fernández-Navarro P, Ramis R. Childhood leukemia and residential proximity to industrial and urban sites. Environ Res. 2015 Jul;140:542-53. doi: 10.1016/j.envres.2015.05.014. Epub 2015 May 27.

PUBMED

Mediterranean Dietary Pattern is Associated with Low Risk of Aggressive Prostate Cancer: MCC-Spain Study

Castelló A, Boldo E, Amiano P, Castaño-Vinyals G, Aragonés N, Gómez-Acebo I, Peiró R, Jimenez-Moleón JJ, Alguacil J, Tardón A, Cecchini L, Lope V, Dierssen-Sotos T, Mengual L, Kogevinas M, Pollán M, Pérez-Gómez B; MCC-Spain Researchers.Mediterranean Dietary Pattern is Associated with Low Risk of Aggressive Prostate Cancer: MCC-Spain Study. J Urol. 2018 Feb;199(2):430-437. doi: 10.1016/j.juro.2017.08.087.

PUBMED

Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21

Fernandez-Navarro P, González-Neira A, Pita G, Díaz-Uriarte R, Tais Moreno L, Ederra M, Pedraz-Pingarrón C, Sánchez-Contador C, Vázquez-Carrete JA, Moreo P, Vidal C, Salas-Trejo D, Stone J, Southey MC, Hopper JL, Pérez-Gómez B, Benitez J, Pollan M. Genome wide association study identifies a novel putative mammographic density locus at 1q12-q21. Int J Cancer. 2015 May 15;136(10):2427-36. doi: 10.1002/ijc.29299.

PUBMED

Obstetric history and mammographic density: a population-based cross-sectional study in Spain (DDM-Spain)

Lope V, Pérez-Gómez B, Sánchez-Contador C, Santamariña MC, Moreo P, Vidal C, Laso MS, Ederra M, Pedraz-Pingarrón C, González-Román I, García-López M, Salas-Trejo D, Peris M, Moreno MP, Vázquez-Carrete JA, Collado F, Aragonés N, Pollán M; DDM-Spain. Obstetric history and mammographic density: a population-based cross-sectional study in Spain (DDM-Spain). Breast Cancer Res Treat. 2012 Apr;132(3):1137-46. doi: 10.1007/s10549-011-1936-x.

PUBMED

Arsenic and chromium topsoil levels and cancer mortality in Spain

Núñez O, Fernández-Navarro P, Martín-Méndez I, Bel-Lan A, Locutura JF, López-Abente G.Arsenic and chromium topsoil levels and cancer mortality in Spain. Environ Sci Pollut Res Int. 2016 Sep;23(17):17664-75. doi: 10.1007/s11356-016-6806-y.

PUBMED

Helicobacter pylori serological biomarkers of gastric cancer risk in the MCC-Spain case-control Study

Fernández de Larrea-Baz N, Pérez-Gómez B, Michel A, Romero B, Lope V, Pawlita M, Fernández-Villa T, Moreno V, Martín V, Willhauck-Fleckenstein M, López-Abente G, Castilla J, Fernández-Tardón G, Dierssen-Sotos T, Santibáñez M, Peiró R, Jiménez-Moleón JJ, Navarro C, Castaño-Vinyals G, Kogevinas M, Pollán M, de Sanjosé S, Del Campo R, Waterboer T, Aragonés N. Helicobacter pylori serological biomarkers of gastric cancer risk in the MCC-Spain case-control Study. Cancer Epidemiol. 2017 Oct;50(Pt A):76-84. doi: 10.1016/j.canep.2017.08.002. Epub 2017 Sep 7.

PUBMED

Environmental metals and cardiovascular disease

Tellez-Plaza M 1, Guallar E 2, Navas-Acien A 3. Environmental metals and cardiovascular disease. BMJ. 2018 Aug 29;362:k3435. doi: 10.1136/bmj.k3435. PubMed PMID: 30158104; PubMed Central PMCID: PMC6283369

PUBMED

Moderate alcohol drinking is not associated with risk of depression in older adult

García-Esquinas E, Ortolá R, Gálan I, Soler-Vila H, Laclaustra M, Rodríguez-Artalejo F. Moderate alcohol drinking is not associated with risk of depression in older adults. Sci Rep. 2018 Jul 31;8(1):11512. doi: 10.1038/s41598-018-29985-4. PubMed PMID: 30065286; PubMed Central PMCID: PMC6068095.

PUBMED

Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study

Domingo-Relloso A, Grau-Perez M, Galan-Chilet I, Garrido-Martinez MJ, Tormos C, Navas-Acien A, Gomez-Ariza JL, Monzo-Beltran L, Saez-Tormo G, Garcia-Barrera T, Dueñas Laita A, Briongos Figuero LS, Martin-Escudero JC, Chaves FJ, Redon J, Tellez-Plaza M. Urinary metals and metal mixtures and oxidative stress biomarkers in an adult population from Spain: The Hortega Study. Environ Int. 2019 Feb;123:171-180. doi: 10.1016/j.envint.2018.11.055. Epub 2018 Dec 5. PubMed PMID: 30529889.

PUBMED

Smoke-Free Legislation in Spain and Prematurity

Simón L, Pastor-Barriuso R, Boldo E, Fernández-Cuenca R, Ortiz C, Linares C, Medrano MJ, Galán I. Smoke-Free Legislation in Spain and Prematurity. Pediatrics. 2017 Jun;139(6). pii: e20162068. doi: 10.1542/peds.2016-2068. Epub 2017 May 17. PubMed PMID: 28562257.

PUBMED

Impact of declining exposure to secondhand tobacco smoke in public places to decreasing smoking-related cancer mortality in the US population

García-Esquinas E, Jiménez A, Pastor-Barriuso R, Jones MR, Perez-Gomez B, Navas-Acien A, Tellez-Plaza M. Impact of declining exposure to secondhand tobacco smoke in public places to decreasing smoking-related cancer mortality in the US population. Environ Int. 2018 Aug;117:260-267. doi: 10.1016/j.envint.2018.05.008. Epub 2018 May 16. PubMed PMID: 29775915; PubMed Central PMCID: PMC6136453.

PUBMED

Individual factors and school-based policies related to adherence to physical activity recommendations in Spanish adolescents

Galán I, Boix R, Medrano MJ, Ramos P, Rivera F, Moreno C. Individual factors and school-based policies related to adherence to physical activity recommendations in Spanish adolescents. Prev Sci. 2014 Aug;15(4):588-99. doi: 10.1007/s11121-013-0407-5. PubMed PMID: 23728581.

PUBMED

Arsenic exposure, diabetes-related genes and diabetes prevalence in a general population from Spain

Grau-Perez M, Navas-Acien A, Galan-Chilet I, Briongos-Figuero LS, Morchon-Simon D, Bermudez JD, Crainiceanu CM, de Marco G, Rentero-Garrido P, Garcia-Barrera T, Gomez-Ariza JL, Casasnovas JA, Martin-Escudero JC, Redon J, Chaves FJ, Tellez-Plaza M. Arsenic exposure, diabetes-related genes and diabetes  prevalence in a general population from Spain. Environ Pollut. 2018 Apr;235:948-955. doi: 10.1016/j.envpol.2018.01.008. Epub 2018 Feb 21. PubMed PMID: 29751399.

PUBMED

Validity of self-reported exposure to second-hand smoke in hospitality venues

Galán I, Mayo E, López MJ, Pérez-Ríos M, Fu M, Martínez-Sánchez JM, Schiaffino A, Moncada A, Montes A, Nebot M, Fernández E. Validity of self-reported exposure to second-hand smoke in hospitality venues. Environ Res. 2014 Aug;133:1-3. doi: 10.1016/j.envres.2014.04.029. Epub 2014 Jun 3. PubMed PMID: 24906061.

PUBMED

In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health Study

Riffo-Campos AL, Fuentes-Trillo A, Tang WY, Soriano Z, De Marco G, Rentero-Garrido P, Adam-Felici V, Lendinez-Tortajada V, Francesconi K, Goessler W, Ladd-Acosta C, Leon-Latre M, Casasnovas JA, Chaves FJ, Navas-Acien A, Guallar  E, Tellez-Plaza M. In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health  Study. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748). pii: 20170084. doi: 10.1098/rstb.2017.0084. PubMed PMID: 29685964; PubMed Central PMCID: PMC5915723.

PUBMED

Alcohol drinking patterns and biomarkers of coronary risk in the Spanish population

Galán I, Valencia-Martín JL, Guallar-Castillón P, Rodríguez-Artalejo F. Alcohol drinking patterns and biomarkers of coronary risk in the Spanish population. Nutr Metab Cardiovasc Dis. 2014 Feb;24(2):189-97. doi: 10.1016/j.numecd.2013.07.002. Epub 2014 Jan 10. PubMed PMID: 24418385.

PUBMED

Hepatitis A outbreak disproportionately affecting men who have sex with men (MSM) in the European Union and European Economic Area

Ndumbi P, Freidl GS, Williams CJ, Mårdh O, Varela C, Avellón A, Friesema I, Vennema H, et al. Hepatitis A outbreak disproportionately affecting men who have sex with men (MSM) in the European Union and European Economic Area, June 2016 to May 2017. Euro Surveill. 2018;23(33):pii=1700641.

PUBMED

Association between meteorological factors and hepatitis A in Spain 2010–2014

Gullón P, Varela C, Martínez EV, Gómez-Barroso D. Association between meteorological factors and hepatitis A in Spain 2010–2014. Environment International 2017 102 230–235.

PUBMED DOI

Non-imported malaria in non-endemic countries: a review of cases in Spain

Velasco E, Gomez-Barroso D, Varela C, Diaz O, Cano R. Non-imported malaria in non-endemic countries: a review of cases in Spain. Malar J. 2017 16:260. DOI 10.1186/s12936-017-1915-8.

PUBMED DOI

Nonmotor symptoms evolution during 24 months of bilateral subthalamic stimulation in Parkinson's disease

1. Dafsari HS, Silverdale M, Strack M, Rizos A, Ashkan K, Mahlstedt P, Sachse L, Steffen J, Dembek TA, Visser-Vandewalle V, Evans J, Antonini A, Martinez-Martin P, Ray-Chaudhuri K, Timmermann L. Nonmotor symptoms evolution during 24 months of bilateral subthalamic stimulation in Parkinson's disease. Mov Disord 2018;33(3):421-30. [doi].PM:29465787. FI: 8,324; Q1

DOI

Risk of transmission of sporadic Creutzfeldt-Jakob disease by surgical procedures: systematic reviews and quality of evidence

2. García López FJ, Ruiz-Tovar M, Almazán-Isla J, Alcalde-Cabero E, Calero M, de Pedro-Cuesta J. Risk of transmission of sporadic Creutzfeldt-Jakob disease by surgical procedures: systematic reviews and quality of evidence. Euro Surveill 2017;22(43). [doi].PM:29090678. FI: 7,127; Q1

DOI

Validation study of the hoehn and yahr scale included in the MDS-UPDRS

3. Martinez-Martin P, Skorvanek M, Rojo-Abuin JM, Gregova Z, Stebbins GT, Goetz CG. Validation study of the hoehn and yahr scale included in the MDS-UPDRS. Mov Disord 2018;33(4):651-2. [doi].PM:29322548. FI: 8,324; Q1

DOI

The long-term direct and indirect economic burden among Parkinson's disease caregivers in the United States

4. Martinez-Martin P, Macaulay D, Jalundhwala YJ, Mu F, Ohashi E, Marshall T, Sail K. The long-term direct and indirect economic burden among Parkinson's disease caregivers in the United States. Mov Disord 2018. [doi].PM:30589953. FI: 8,324; Q1

DOI

Relationship of Nocturnal Sleep Dysfunction and Pain Subtypes in Parkinson's Disease

5. Martinez-Martin P, Rizos AM, Wetmore JB, Antonini A, Odin P, Pal S, Sophia R, Carroll C, Martino D, Falup-Pecurariu C, Kessel B, Andrews T, Paviour D, Trenkwalder C, Chaudhuri KR. Relationship of Nocturnal Sleep Dysfunction and Pain Subtypes in Parkinson's Disease. Mov Disord Clin Pract 2019;6(1):57-64. doi: 10.1002/mdc3.12694;doi: 10.1002/mdc3.12694.. FI: 8,324; Q1

DOI

Rating Scales and Performance-based Measures for Assessment of Functional Ability in Huntington's Disease: Critique and Recommendations

6. Mestre TA, Busse M, Davis AM, Quinn L, Rodrigues FB, Burgunder JM, Carlozzi NE, Walker F, Ho AK, Sampaio C, Goetz CG, Cubo E, Martinez-Martin P, Stebbins GT. Rating Scales and Performance-based Measures for Assessment of Functional Ability in Huntington's Disease: Critique and Recommendations. Mov Disord Clin Pract 2018;5(4):361-72. [doi];MDC312617 [pii].PM:30363510. FI: 8,324; Q1

DOI

Rating scales for cognition in Huntington's disease: Critique and recommendations

7. Mestre TA, Bachoud-Levi AC, Marinus J, Stout JC, Paulsen JS, Como P, Duff K, Sampaio C, Goetz CG, Cubo E, Stebbins GT, Martinez-Martin P. Rating scales for cognition in Huntington's disease: Critique and recommendations. Mov Disord 2018;33(2):187-95. [doi].PM:29278291. FI: 8,324; Q1

DOI

The Neuropsychiatric Fluctuations Scale for Parkinson's Disease: A Pilot Study

8. Schmitt E, Krack P, Castrioto A, Klinger H, Bichon A, Lhommee E, Pelissier P, Fraix V, Thobois S, Moro E, Martinez-Martin P. The Neuropsychiatric Fluctuations Scale for Parkinson's Disease: A Pilot Study. Mov Disord Clin Pract 2018;5(3):265-72. [doi];MDC312607 [pii].PM:30363450. FI: 8,324; Q1

DOI

Global scales for cognitive screening in Parkinson's disease: Critique and recommendations

9. Skorvanek M, Goldman JG, Jahanshahi M, Marras C, Rektorova I, Schmand B, van DE, Goetz CG, Weintraub D, Stebbins GT, Martinez-Martin P. Global scales for cognitive screening in Parkinson's disease: Critique and recommendations. Mov Disord 2018;33(2):208-18. [doi].PM:29168899. FI: 8,324; Q1

DOI

Reply: MoCA for cognitive screening in Parkinson's disease: Beware of floor effect

10. Skorvanek M, Goldman JG, Jahanshahi M, Marras C, Rektorova I, Schmand B, van DE, Goetz CG, Weintraub D, Stebbins GT, Martinez-Martin P. Reply: MoCA for cognitive screening in Parkinson's disease: Beware of floor effect. Mov Disord 2018;33(3):499-500. [doi].PM:29460975. FI: 8,324; Q1

Detection of spatial aggregation of cases of cáncer from data on patients and health centres contained in the Minimum Basic Data Set

Fernandez-Navarro, Pablo; et al. 2Detection of spatial aggregation of cases of cáncer from data on patients and health centres contained in the Minimum Basic Data Set GEOSPATIAL HEALTH. UNIV NAPLES FEDERICO II. 13-1, pp.86-92

PUBMED DOI

Patterns of Differentially Expressed circRNAs in Human Thymocytes.

Patterns of Differentially Expressed circRNAs in Human Thymocytes. López-Nieva P, Fernández-Navarro P, Cobos-Fernández MÁ, González-Vasconcellos I, Sánchez Pérez R, Aroca Á, Fernández-Piqueras J, Santos J. Noncoding RNA. 2022 Mar 30;8(2):26. doi: 10.3390/ncrna8020026. PMID: 35447889 Free PMC article.

PUBMED DOI

Industrial pollution and cancer in Spain: An important public health issue

Fernandez-Navarro, Pablo; et al. 2017. Industrial pollution and cancer in Spain: An important public health issue Environmental research. 159, pp.555-563. ISSN 0013-9351.

PUBMED DOI

Association between heavy metal and metalloid levels in topsoil and cancer mortality in Spain

Núñez, O.; et al. 2017. Association between heavy metal and metalloid levels in topsoil and cancer mortality in Spain.Environmental science and pollution research international. 24-8, pp.7413-7421. ISSN 1614-7499.

PUBMED DOI

The Minimum Basic Data Set (MBDS) as a tool for cancer epidemiological surveillance

Fernández Navarro, P.; et al. 2016. The Minimum Basic Data Set (MBDS) as a tool for cancer epidemiological surveillance. European journal of internal medicine. 34, pp.94-97. ISSN 1879-0828.

PUBMED DOI

User profiles of an electronic mental health tool for ecological momentary assessment: MEmind

Barrigón, ML.; et al. 2017. User profiles of an electronic mental health tool for ecological momentary assessment: MEmind.International journal of methods in psychiatric research. 26-1. ISSN 1557-0657.

PUBMED DOI

SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms.

SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms. Lahera A, López-Nieva P, Alarcón H, Marín-Rubio JL, Cobos-Fernández MÁ, Fernández-Navarro P, Fernández AF, Vela-Martín L, Sastre I, Ruiz-García S, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M. Br J Haematol. 2023 May;201(4):718-724. doi: 10.1111/bjh.18694. Epub 2023 Feb 14. PMID: 36786170

PUBMED DOI

Rural-urban gradients and all-cause, cardiovascular and cancer mortality in Spain using individual data.

Rural-urban gradients and all-cause, cardiovascular and cancer mortality in Spain using individual data. Ayuso-Álvarez A, Ortiz C, López-Cuadrado T, Rodríguez-Blázquez C, Fernández-Navarro P, González-Palacios J, Damián J, Galán I. SSM Popul Health. 2022 Sep 19;19:101232. doi: 10.1016/j.ssmph.2022.101232. eCollection 2022 Sep. PMID: 36188419 Free PMC article.

PUBMED DOI

RANking SPAtial areas of risk in spatial surveillance

RANking SPAtial areas of risk in spatial surveillance

PUBMED DOI

RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas BMC CANCER

Lopez-Nieva, Pilar; et al. 2018. RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas BMC CANCER. BMC. 18. ISSN 1471-2407.

PUBMED DOI

The Role of Environmental Factors in Lyme Disease Transmission in the European Union: A Systematic Review

Christine Giesen, Daniel Cifo, Diana Gomez-Barroso, et al. Trop Med Infect Dis . 2024 May 15;9(5):113.

PUBMED DOI

Epidemiology of Q fever in humans in four selected regions, Spain, 2016 to 2022

Cifo D, Estévez-Reboredo RM, González-Barrio D, et al. Euro Surveill. 2024 Jul;29(27):2300688.

PUBMED DOI

Excess mortality in Europe coincides with peaks of COVID-19, influenza and respiratory syncytial virus (RSV), November 2023 to February 2024

Sarah K Nørgaard, Jens Nielsen, Anne Christine Nordholm, et al. Euro Surveill . 2024 Apr;29(15):2400178.

PUBMED DOI

The impact of meteorological factors on tuberculosis incidence in Spain: a spatiotemporal analysis

María Del Mar Díez Galán, Lidia Redondo-Bravo, Diana Gómez-Barroso, et al. Epidemiol Infect . 2024 Mar 20:152:e58.

PUBMED DOI

Modeling the Regional Distribution of International Travelers in Spain to Estimate Imported Cases of Dengue and Malaria: Statistical Inference and Validation Study

David García-García, Beatriz Fernández-Martínez, Frederic Bartumeus, Diana Gómez-Barroso. JMIR Public Health Surveill . 2024 May 27:10:e51191.

PUBMED DOI

Situación epidemiológica prepandémica de la campilobacteriosis en España entre los años 2013-2019

Carbajo Otero A, Guerrero Vadillo M, León Gómez I, Varela Martínez MC. Situación epidemiológica prepandémica de la campilobacteriosis en España entre los años 2013-2019. Rev Salud ambient. 2023; 23(2):131-140.

First cross-border outbreak of foodborne botulism in the European Union associated with the consumption of commercial dried roach (Rutilus rutilus)

Hendrickx D, Varela Martínez C, Contzen M, Wagner-Wiening C, Janke K-H, Hernando Jiménez P, Massing S, Pichler J, Tichaczek-Dischinger P, Burckhardt F, Stark K, Katz K, Jurke A, Thole S, Carbó R, del Pobil Ferré MP, Nieto M, Zamora MJ, Sisó A, Pallares García P, Valdezate S, Schaade L, Worbs S, Dorner BG, Frank C and Dorner MB. First cross-border outbreak of foodborne botulism in the European Union associated with the consumption of commercial dried roach (Rutilus rutilus). Front. Public Health 2023;10:1039770.

PUBMED DOI

Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019)

Guerrero-Vadillo M, Peñuelas Martínez M, Varela Martínez C. Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019). BES [Internet]. 24 de enero de 2022 ;29(2). Disponible en: //revista.isciii.es/index.php/bes/article/view/1124

Severity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014

Severi E, Georgalis L, Pijnacker R, Veneti L, Turiac IA, Chiesa F, Rizzo C, Martinelli D, Vold L, Herrador BG, Martinez CV, Sanchez EVM, Semenza JC, Lopalco P, Dahlström LA, Giesecke J. Severity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014. International Journal of Infectious Diseases 2022; 118, 34-43

PUBMED DOI

Investigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022

Larkin L., de la Gandara M.P., Hoban A., Pulford C., Silva N.J.-D., de Valk H., Browning L., Falkenhorst G., Simon S., Lachmann R., Dryselius R., Karamehmedovic N., Börjesson S., van Cauteren D., Laisnez V., Mattheus W., Pijnacker R., van den Beld M., Mossong J., Ragimbeau C., Vergison A., Brandal L.T., Lange H., Garvey P., Nielsen C.S., León S.H., Varela C., Chattaway M., Weill F.-X., Brown D., McKeown P. Investigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022. Euro Surveill2022;27(15):pii=2200314.

PUBMED DOI

Botulism in Spain: Epidemiology and Outcomes of Antitoxin Treatment, 1997-2019

Peñuelas M, Guerrero-Vadillo M, Valdezate S, Zamora MJ, Leon-Gomez I, Flores-Cuéllar Á, Carrasco G, Díaz-García O, Varela C. Botulism in Spain: Epidemiology and Outcomes of Antitoxin Treatment, 1997-2019. Toxins (Basel). 2022 Dec 20;15(1):2.

PUBMED DOI

Previcet Working Group On Viral Hepatitis. Hepatitis A Outbreak Characteristics: A Comparison of Regions with Different Vaccination Strategies, Spain 2010-2018

Domínguez A, Varela C, Soldevila N, Izquierdo C, Guerrero M, Peñuelas M, Martínez A, Godoy P, Borràs E, Rius C, Torner N, Avellón AM, Castilla J, Previcet Working Group On Viral Hepatitis. Hepatitis A Outbreak Characteristics: A Comparison of Regions with Different Vaccination Strategies, Spain 2010-2018. Vaccines (Basel). 2021 Oct 20;9(11):1214.

PUBMED DOI

Statement of Peer Review

Bygvraa, D.A.; Crespi, S.; Cornejo, M.D.; De Marez, L.; Hadjichristodoulou, C.; Harth, V.; Jelicic, P.; Klein, J.; Michaelakis, A.;Mouchtouri, V.; et al. Statement of Peer Review. Med. Sci. Forum 2023;13, 34.

DOI

Evaluación de la sensibilidad del sistema de vigilancia del botulismo en España entre 1997 y 2019

Peñuelas M, Guerrero-Vadillo M, Díaz-García O, García-García D, Varela C. Evaluación de la sensibilidad del sistema de vigilancia del botulismo en España entre 1997 y 2019. BES [Internet]. 31 de marzo de 2023;31(1):37-43. Disponible en: //revista.isciii.es/index.php/bes/article/view/1285

Vigilancia epidemiológica de Shigelosis en España, 2016-2021

Guerrero-Vadillo M, Peñuelas M, Herrera León S, Suarez Rodriguez B, Díaz A, Guzmán Herrador B, et al. Vigilancia epidemiológica de Shigelosis en España, 2016-2021. BES [Internet]. 21 de marzo de 2022;29(8):90-8. Disponible en: //revista.isciii.es/index.php/bes/article/view/1201

Brotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020

Chong A, Peñuelas M, Guerrero M, Cabezas C, Díaz O, Martín C, et al. Brotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020. BES [Internet]. 29 de marzo de 2022;29(5):53-6. Disponible en: //revista.isciii.es/index.php/bes/article/view/1157

Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022

Vidal A.R., Vaughan A., Innocenti F., Colombe S., Nerlander L., Rachwal N., Ciancio B.C., Mougkou A., Carvalho C., Delgado E., Mook P., De Muylder G., Peeters M., Tenev T., Golkocheva-Markova E., Jensen V.V.S., Koch A., Figoni J., Brouard C., Nikolopoulou G., Zisouli A., Murphy N., Broderick A., Goldberg L., Rich R., Sagie L.H., Tosti M.E., Suligoi B., Joosten R., Pijnacker R., Fjeldheim I., Heen E., Stȩpień M., Polański P., Marinho R.T., Martins J.V., Varela C., Avellón A., Andersson E., Mörk M.J., Mandal S., Watson C., Coughlan L., Chand M., Neill C., Bradley D.T., Li K., O'Leary M., McInnes N., Williams C.J., Moore C., Gjini A., Duffell E., Pebody R.. Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022. Euro Surveill. 2022;27(31):pii=2200483.

PUBMED DOI

Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak

Guerrero-Vadillo M, Peñuelas M, Domínguez Á, Godoy P, Gómez-Barroso D, Soldevila N, Izquierdo C, Martínez A, Torner N, Avellón A, Rius C, Varela C. Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak. Int J Environ Res Public Health. 2022 Dec 14;19(24):16775.

PUBMED DOI

Contenidos con Investigacion Subunidad de Bioinformática y Gestión de Datos .

Listado de personal

Información adicional

Los objetivos principales de esta subunidad son:

  • Prestar apoyo en diseño y gestión de bases de datos y aplicaciones para dispositivos móviles/aplicaciones web
  • Mantener los servidores de información de enfermedades crónicas y de mortalidad con los que cuenta el CNE (Servidor de Información Epidemiológica on-line “ARIADNA” (https://ariadna.isciii.es/), Servidor de Información Epidemiológica on-line “RAZIEL” (https://raziel.isciii.es/).
  • Dar soporte técnico y logístico a la investigación en enfermedades crónicas desde un punto de vista genético y bioinformático (Gestión y desarrollo de aplicaciones de anotación para marcadores genéticos (SNPs, MicroRNA, etc) y extracción de información de estos, Tools de recodificación de identificadores de marcadores y cruces de bases de datos genómicas y representación de datos genómicos).
  • Investigar y desarrollar métodos relacionados con instrumentos para la obtención de información y transmisión de esta en la investigación epidemiológica, la integración de fuentes de información y datos epidemiológicos y las infraestructuras de computación, almacenaje y transferencia de datos en salud.

Contacto
Tel.: +34 91 822 26 44
Email: pfernandezn@isciii.es

 

Contenidos con Investigacion Subunidad de Bioinformática y Gestión de Datos .