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Investigación

Vaccine-Preventable Diseases

Líneas de investigación

Enfermedades de transmisión respiratoria

Enfermedades transmitidas por agua y alimentos, vigilancia epidemiológica, prevención y control

Envejecimiento, Neurodegeneración y Salud Mental

Envejecimiento, Neurodegeneración y Salud Mental

Epidemiología de Enfermedades Cardiovasculares y Metabólicas

Epidemiología del Cáncer y Ambiental

Subunidad de Bioinformática y Gestión de Datos

Unidad de la Cohorte de la Red de Investigación en Sida (CoRIS)

Vigilancia e Investigación del VIH e ITS

Medio Ambiente, Fragilidad y Multimorbilidad en el Envejecimiento

  • Impacto de factores ambientales y sociales sobre la acumulación de déficits en salud, la multimorbilidad y el deterioro de la función física en el adulto mayor
  • Determinantes conductuales de dolor crónico y deterioro funcional en el adulto mayor
  • Determinantes de discapacidad y mortalidad en población adulta: enfoques metodológicos avanzados
  • Identificación de biomarcadores asociados a la acumulación de déficits en salud, la multimorbilidad y el deterioro funcional en el adulto mayor

Contaminación Ambiental y Cáncer

  • Contaminación ambiental y cáncer
  • Factores ambientales y densidad mamográfica
  • Metodología de exposición a contaminación ambiental

Nutrición, Estilos de Vida, Inflamación y Cáncer

  • Factores dietéticos y de estilos de vida asociados al cáncer y a la inflamación sistémica
  • Calidad de vida relacionada con la salud y cáncer 
  • Determinantes de la densidad mamográfica
  • Determinantes de los estilos de vida y desarrollo de intervenciones para la promoción de la salud
  • Innovación en la medición de la exposición dietética
  • Calidad de la dieta y el comportamiento alimentario

Exposoma y Salud Infantil

  • Medioambiente e incidencia de cáncer infantil (MAICI)
  • Contaminación atmosférica y efectos al nacimiento (QALIOPE)
  • Medioambiente y salud urbana 

Análisis Causal y Método Epidemiológico

  • Modelización 
  • Machine learning
  • Inferencia causal 

 

Epidemiología Integradora y Salud Cardiometabólica

  • Desarrollo de nuevos métodos de análisis para integrar factores genéticos, ambientales y conductuales
  • Diseño de estrategias de prevención y control basadas en biomarcadores y epidemiología molecular
  • Mecanismos moleculares y rutas funcionales en la relación entre ambiente y salud

Envejecimiento Saludable y Resultados de Salud

  • Impacto del edadismo en la salud y bienestar de la población mayor
  • Calidad de vida y calidad de vida relacionada con la salud en población mayor
  • Resultados de salud informados por los pacientes (PRO) y validación de escalas
  • Aspectos psicosociales de las enfermedades neurodegenerativas
  • Cuidados informales y personas mayores

Estudios de Comportamiento en Salud

  • Estrategias de prevención y control basadas en los estudios del comportamiento y las enfermedades infecciosas y tropicales (incluyendo OneHealth)
  • Estrategias de prevención y control basadas en el comportamiento de las enfermedades crónicas y la nutrición 
  • Preparación para pandemias y desastres naturales
  • Estrategias de prevención y control basadas en el estudio del comportamiento de los profesionales sanitarios 

IRAS – Infecciones Relacionadas con la Asistencia Sanitaria y Resistencias frente a Antimicrobianos

  • Investigación en la epidemiología de las Infecciones Relacionadas con la Asistencia Sanitaria (IRAS). Valorar la calidad asistencial en cirugías frecuentemente realizadas en España usando como indicador la incidencia de IRAS.
    • Variación geográfica de la carga de enfermedad por IRAS en hospitales.
    • Estimación del impacto de la organización hospitalaria en la incidencia de IRAS.

  • Investigación en la epidemiología de las Resistencias a Antimicrobianos (RAM).
    • Valoración de la idoneidad de los tratamientos antimicrobianos en pacientes mayores con patologías crónicas de base.
    • Estimación de costes asociados al manejo de las infecciones de microrganismos resistentes.
    • Generación de modelos de predicción de riesgo de infección y de riesgo de infección por microorganismo resistentes.

  • El “convenio entre el Instituto de Salud Carlos III O.A., M.P. y Clínica Barceloneta S.A. para el desarrollo de actividades relacionadas con el estudio del impacto de los antimicrobianos en la incidencia de resistencias en pacientes mayores atendidos en hospitales de atención intermedia de Barcelona”. Número de expediente: RCN-CNU202400125 Vigente hasta el 04/10/2028
  • El proyecto coordinado “Desarrollo de Infraestructuras ISCIII para la creación, estandarización y producción de fagos útiles en Infecciones bacterianas pulmonares crónicas. (DISCIII-Phage)” Número de expediente: COOP24CIII/00010. Vigente hasta el 30 de Junio de 2028. Programa COOPERA-ISCIII para la realización de proyectos coordinados estratégicos transversales en el marco de la AES intramural (AESI) 2024.
  • El proyecto “Salud mental y vulnerabilidad a infecciones en personas mayores hospitalizadas”. Número de expediente: PI25CIII/00011 Vigente hasta el 31 de diciembre de 2028. Convocatoria Proyectos de I+D+I en salud-ISCIII de la convocatoria 2025 de la Acción Estratégica en Salud Intramural.

Análisis espacial e impacto ambiental en enfermedades transmisibles

  1. Análisis espacio temporal de enfermedades transmisibles
  2. Análisis del impacto ambiental en la transmisión y difusión de enfermedades infecciosas
  3. Mortalidad diaria, factores meteorológicos y cambio climático

Enfermedades Prevenibles por Vacunación

  • Vigilancia en la fase avanzada de erradicación de la poliomielitis. Vigilancia de la Parálisis Flácida Aguda.
  • Vigilancia y epidemiología del sarampión y rubeola en fase de post-eliminación en España. Evaluación de nuevas herramientas en la vigilancia genómica del sarampión.
  • Vigilancia epidemiológica y virológica de la parotiditis en España: patrones de circulación del virus de la parotiditis en el contexto de brotes epidémicos.
  • Estudio de la reemergencia de tosferina en España después de la pandemia por COVID-19. Impacto de la vacunación de las gestantes en la gravedad de la tosferina en lactantes.
  • Variaciones en la epidemiología de la varicela y del herpes zóster tras la inclusión de la vacunación en el calendario.
  • Análisis de la evolución de los serotipos que causan la enfermedad neumocócica invasiva (ENI) en la actualidad, para adaptar las estrategias de prevención y control de la enfermedad
  • Análisis comparativo de las tasas de incidencia de enfermedad meningocócica invasiva en las distintas Comunidades Autónomas. Evaluación del sistema de vigilancia de la enfermedad meningocócica invasiva.
  • Vigilancia de los casos de enfermedad invasiva por Haemophilus influenzae tipo b (Hib) tras el cambio de pauta de vacunación en el programa de vacunación aprobado por el Sistema Interterritorial del Sistema Nacional de Salud en 2017. Análisis del incremento de casos de Hi capsulares (distintos a Hib) y no capsulares de los últimos años

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Publicaciones destacadas

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Exploring the effect of clinical case definitions on influenza vaccine effectiveness estimation at primary care level: Results from the end-of-season 2022-23 VEBIS multicentre study in Europe.

Maurel M, Mazagatos C, Goerlitz L, Oroszi B, Hooiveld M, Machado A, et al. Vaccine. 2024 Jun 11;42(16):3547–54.

PUBMED DOI

Glyphosate exposure, muscular health and functional limitations in middle-aged and older adults

Jauregui-Zunzunegui S, Rodríguez-Artalejo F, Tellez-Plaza M, García-Esquinas E. Glyphosate exposure, muscular health and functional limitations in middle-aged and older adults. Environ Res. 2024 Jun 15;251(Pt 1):118547.

PUBMED DOI

Residential exposure to traffic pollution and mammographic density in premenopausal women.

Jiménez T, Domínguez-Castillo A, Fernández de Larrea-Baz N, Lucas P, Sierra MÁ, Salas-Trejo D, Llobet R, Martínez I, Pino MN, Martínez-Cortés M, Pérez-Gómez B, Pollán M, Lope V, García-Pérez J. Residential exposure to traffic pollution and mammographic density in premenopausal women. Sci Total Environ. 2024 Jun 10;928:172463.

PUBMED DOI

Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews

Plans-Beriso E, Babb-de-Villiers C, Petrova D, Barahona-López C, Diez-Echave P, Hernández OR, Fernández-Martínez NF, Turner H, García-Ovejero E, Craciun O, Fernández-Navarro P, Fernández-Larrea N, García-Esquinas E, Kuhn I, Jiménez-Planet V, Moreno V, Rodríguez-Artalejo F, Sánchez MJ, Pollan-Santamaria M, Blackburn L, Kroese M, Pérez-Gómez B. Biomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews. Syst Rev. 2024 Jun 1;13(1):147.

PUBMED DOI

Sexually transmitted infections care service provision in Spain: Characteristics, diagnostic capabilities, and training.

Gómez-Castellá J, Nuño N, Diaz A, del Amo J, the Spanish HIV/STI Coordinators Group. Prev Med Rep . 2025 May 2:54:103086.

PUBMED DOI

Increased mortality and morbidity risk in people with early HIV care interruption in Spain.

Izquierdo R, Rava M, Gutiérrez F, García-Fraile LJ, Riera M, Imaz A, Sotomayor C, Reus S, Rubio R, Iribarren JA, Jarrín I; CoRIS Cohort. AIDS. 2025 Jul 15;39(9):1224-1234.

PUBMED DOI

Marked increase in cryptosporidiosis cases, Spain, 2023. Euro Surveill. 2024;29(28):2300733.

Peñuelas Martínez M, Carmena D, Guzmán Herrador BR, et al.

DOI

Changes in mental health diagnosis and healthcare use in seven European countries before and during the COVID-19 pandemic (2017-21).

Rodríguez-Blazquez C, Aldridge SJ, Bernal-Delgado E, Calomfirescu C, Dolanski-Aghamanoukjan L, Estupiñán-Romero F, Gissler M, Beate G, Idavain J, Larose TL, Lyons RA, Mathis-Edenhofer S, Miller K, Misiņš J, Radulescu S, Rätsep M, Sagerschnig S, Sandu P, Šitcs J, Pavlovska Z, Thißen M, Tolonen H, Garriga C, Forjaz MJ. Changes in mental health diagnosis and healthcare use in seven European countries before and during the COVID-19 pandemic (2017-21). Eur J Public Health. 2025 Jun 1;35(3):484-490.

PUBMED DOI

A growing disconnection from nature. Urgent call to action for a nature prescription global health alliance.

Ortega-García JA, Martínez-Gómez C, Bach A, Benitez-Rodríguez L, Ramis R; en representación de la Alianza GRSIA. A growing disconnection from nature. Urgent call to action for a nature prescription global health alliance. An Pediatr (Engl Ed). 2024 Jun;100(6):e10-e12.

PUBMED DOI

Recent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study

López-Cuadrado T, Susser E, Martínez-Alés G. Recent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study. Bipolar Disord. 2024 Dec;26(8):801-809.

PUBMED DOI

Association Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic.

Agurto-Ramírez A, Pino-Rosón C, Ayala A, Falcón M, Rodríguez-Blázquez C, Forjaz MJ, Romay-Barja M. Association Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic. Int J Public Health. 2023 Sep 26;68:1606049.

PUBMED DOI

Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study.

Galán I, Fontán J, Ortiz C, López-Cuadrado T, Téllez-Plaza M, García-Esquinas E. Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study. Addict Behav. 2024 Nov;158:108108.

PUBMED DOI

Association of miR-126-3p, miR-1260b and miR-374a-5p with the incidence of heart failure in a population-based cohort: the Hortega Follow-Up Study.

Grau-Perez M, Martinez-Arroyo O, Rubia-Martinez M, Flores-Chova A, Rodriguez-Hernandez Z, Fernández-Navarro P, Gonzalez-Neira A, Alonso MR, Pita G, Pineda S, Martin-Escudero JC, Ortega A, Redon J, Tellez-Plaza M, Cortes R. Association of miR-126-3p, miR-1260b and miR-374a-5p with the incidence of heart failure in a population-based cohort: the Hortega Follow-Up Study. Eur J Intern Med. 2025 May;135:118-125.

PUBMED DOI

Measles Among the Foreign-Born Population Residing in Spain, 2014–2022: Missed Opportunities for Vaccination.

Noemí López-Perea, Teresa López-Cuadrado, Aurora Fernández-García, Juan E. Echevarría, Josefa Masa-Calles. Vaccines, 2024

DOI

Approximate Bayesian inference for multivariate point pattern analysis in disease mapping

Palmí-Perales F, Gómez-Rubio V, López-Abente G, Ramis R, Sanz-Anquela JM, Fernández-Navarro P. Approximate Bayesian inference for multivariate point pattern analysis in disease mapping. Biom J. 2021 Mar;63(3):632-649.

PUBMED DOI

Consumption patterns and key motivational drivers: an analysis of food behavior in Spanish households

Beltrán-de-Miguel B, Del-Pozo-de-la-Calle S, Cuadrado-Vives C, Ruiz-Moreno E. Consumption patterns and key motivational drivers: an analysis of food behavior in Spanish households. Front Nutr. 2025 Jun 23;12:1526957.

PUBMED DOI

Exposure to green spaces, cardiovascular risk biomarkers and incident cardiovascular disease in older adults: The Seniors-Enrica II cohort

Scheer C, Plans-Beriso E, Pastor-Barriuso R, Ortolá R, Sotos-Prieto M, Cabañas-Sánchez V, Gullón P, Ojeda Sánchez C, Ramis R, Fernández-Navarro P, Rodríguez-Artalejo F, García-Esquinas E. Exposure to green spaces, cardiovascular risk biomarkers and incident cardiovascular disease in older adults: The Seniors-Enrica II cohort. Environ Int. 2024 Mar;185:108570.

PUBMED DOI

Mammographic density in the environs of multiple industrial sources.

Jiménez T, Pollán M, Domínguez-Castillo A, Lucas P, Sierra MÁ, Castelló A, Fernández de Larrea-Baz N, Lora-Pablos D, Salas-Trejo D, Llobet R, Martínez I, Pino MN, Martínez-Cortés M, Pérez-Gómez B, Lope V, García-Pérez J. Mammographic density in the environs of multiple industrial sources. Sci Total Environ. 2023 Jun 10;876:162768.

PUBMED DOI

Toenail zinc as a biomarker: Relationship with sources of environmental exposure and with genetic variability in MCC-Spain study

Gutiérrez-González E, Fernández-Navarro P, Pastor-Barriuso R, García-Pérez J, Castaño-Vinyals G, Martín-Sánchez V, Amiano P, Gómez-Acebo I, Guevara M, Fernández-Tardón G, Salcedo-Bellido I, Moreno V, Pinto-Carbó M, Alguacil J, Marcos-Gragera R, Gómez-Gómez JH, Gómez-Ariza JL, García-Barrera T, Varea-Jiménez E, Núñez O, Espinosa A, Molina de la Torre AJ, Aizpurua-Atxega A, Alonso-Molero J, Ederra-Sanz M, Belmonte T, Aragonés N, Kogevinas M, Pollán M, Pérez-Gómez B. Toenail zinc as a biomarker: Relationship with sources of environmental exposure and with genetic variability in MCC-Spain study. Environ Int. 2022 Nov;169:107525.

PUBMED DOI

SIPrEP: a tool to monitor HIV pre-exposure prophylaxis in Spain.

Enferm Infecc Microbiol Clin (Engl Ed). 2025; 43(8):515-522. Iniesta C, Hernando V, Jarrín I, Pérez de la Cámara S, de la Torre J, Villanueva V, Mayorga MI, Belda J, Soteras M, Torres Lana A, Echevarria A, Monteagudo O, Marcos H, Ben Cheikh W, Portocarrero-Núñez JA, Álvarez-del Arco D, Diaz A, del Amo J y SIPrEP Working Group.

PUBMED DOI

Should we measure quality of life among people with HIV? A multicentre survey of physicians' opinions in Spain.

Izquierdo R, Suárez-García I, Gómez-García T, Marco-Sánchez C, Puente-Ferreiro J, Moreno C, Diaz A, Cabello-Clotet N, Vinuesa D, Blanco JL, Melús E, Gómez-Ayerbe C, Olalla J, Riera M, Bernardino JI, de López Bernaldo de Quirós JC, Moreno S, Jarrín I; CoRIS cohort.

PUBMED DOI

Brotes de transmisión alimentaria e hídrica en España, 2018-2022. BES [Internet]. 29 de julio de 2024 [citado 31 de octubre de 2024];32(2):61-73.

Sanz-Olea E, Peñuelas M, Guerrero-Vadillo M, Sastre-García M, Díaz O, Cano-Portero R, et al.

DOI

European HIV continuum of care working group. The HIV continuum of care in European Union countries in 2013: data and challenges

Gourlay A, Noori T, Pharris A, Axelsson M, Costagliola D, Cowan S, Croxford S, d'Arminio Monforte A, Del Amo J, Delpech V, Díaz A, Girardi E, Gunsenheimer-Bartmeyer B, Hernando V, Jose S, Leierer G, Nikolopoulos G, Obel N, Op de Coul E, Paraskeva D, Reiss P, Sabin C, Sasse A, Schmid D, Sonnerborg A, Spina A, Suligoi B, Supervie V, Touloumi G, Van Beckhoven D, van Sighem A, Vourli G, Zangerle R, Porter K; European HIV continuum of care working group. The HIV continuum of care in European Union countries in 2013: data and challenges. Clin Infect Dis. 2017; 64(12)1644-56

PUBMED DOI

Comparative severity of COVID-19 cases caused by Alpha, Delta or Omicron SARS-CoV-2 variants and its association with vaccination.

Varea-Jiménez E, Aznar Cano E, Vega-Piris L, Martínez Sánchez EV, Mazagatos C, García San Miguel Rodríguez-Alarcón L, et al. Enfermedades Infecc Microbiol Clin Engl Ed. 2024 Apr;42(4):187–94.

PUBMED DOI

Development and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children.

Pons R, Pearson TS, Perez-Dueñas B, Garcia-Cazorla A, Kurian MA, Dalivigka Z, Zouvelou V, Outsika C, Kokkinou E, Sigatullina-Bondarenko M, Darling A, O'Callaghan MDM, Spaull R, Steel DBD, Salamou E, Forjaz MJ, Rodriguez-Blazquez C. Development and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children. Mov Disord. 2025 Aug;40(8):1669-1679.

PUBMED DOI

Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.

Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero JC, Ramis R. Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study. Antioxidants (Basel). 2023 Dec 15;12(12):2122.

PUBMED DOI

Hospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study

Vázquez-Giraldo P, Muñoz-Sanjosé A, López-Cuadrado T. Hospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study. Int J Eat Disord. 2024 Nov;57(11):2299-2305.

PUBMED DOI

Risk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.

Ayuso-Álvarez A, Blasco Hernández T, Benito Llanes A. Percepción del riesgo de los profesionales sanitarios ante el primer caso de infección secundaria por ébola en España [Risk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.]. Rev Esp Salud Publica. 2021 Sep 7;95:e202109136.

PUBMED

Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults.

Rodriguez-Hernandez Z, Bel-Aguilar J, Moreno-Franco B, Grau-Perez M, Redon J, Gomez-Ariza JL, Garcia-Barrera T, Olmedo P, Gil F, Cenarro A, Civeira F, Puzo J, Casasnovas JA, Banegas JR, Sotos-Prieto M, Ortola R, Laclaustra M, Rodriguez-Artalejo F, Garcia-Esquinas E, Tellez-Plaza M, Pastor-Barriuso R. Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults. Nutr Diabetes. 2025 Feb 13;15(1):5.

PUBMED DOI

The future burden of type 2 diabetes in Belgium: a microsimulation model.

Mertens E, Ocira J, Sagastume D, Vasquez MS, Vandevijvere S, Peñalvo JL. The future burden of type 2 diabetes in Belgium: a microsimulation model. Popul Health Metr. 2024 Apr 23;22(1):8.

PUBMED DOI

Reduced pertussis disease severity in infants following the introduction of pertussis vaccination of pregnant women in Spain, 2015-2019.

Parisi A, Nuñez O, López-Perea N, Masa-Calles J. Vaccine. 2024 Mar 25:S0264-410X(24)00315-3.

DOI

Different spatial pattern of municipal prostate cancer mortality in younger men in Spain

Rodriguez-Sanchez L, Fernández-Navarro P, López-Abente G, Nuñez O, Fernández de Larrea-Baz N, Jimenez-Moleón JJ, Páez Borda Á, Pollán M, Perez-Gomez B. Different spatial pattern of municipal prostate cancer mortality in younger men in Spain. PLoS One. 2019 Jan 25;14(1):e0210980.

PUBMED DOI

Determinants of Adherence to World Cancer Research Fund/American Institute for Cancer Research Recommendations in Women with Breast Cancer

Pachón Olmos V, Pollán M, Fernández de Larrea-Baz N, Fernández-Morata J, Ruiz-Moreno E, García-Pérez J, Castelló A, Sierra MÁ, Lucas P, Alonso-Ledesma I, Stradella A, Cantos B, Ramón Y Cajal T, Santisteban M, Seguí MÁ, Santaballa Bertrán A, Granja M, Camps-Herrero J, Recalde S, Mendez M, Calvo Verges N, Pérez-Gómez B, Pastor-Barriuso R, Lope V. Determinants of Adherence to World Cancer Research Fund/American Institute for Cancer Research Recommendations in Women with Breast Cancer. Cancers (Basel). 2025 Feb 19;17(4):708.

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Selenium and impaired physical function in US and Spanish older adults

García-Esquinas E, Carrasco-Rios M, Ortolá R, Sotos Prieto M, Pérez-Gómez B, Gutiérrez-González E, Banegas JR, Queipo R, Olmedo P, Gil F, Tellez-Plaza M, Navas-Acien A, Pastor-Barriuso R, Rodríguez-Artalejo F. Selenium and impaired physical function in US and Spanish older adults. Redox Biol. 2021 Jan;38:101819.

PUBMED DOI

Residential proximity to industrial pollution and mammographic density.

Jiménez T, Pollán M, Domínguez-Castillo A, Lucas P, Sierra MÁ, Castelló A, Fernández de Larrea-Baz N, Lora-Pablos D, Salas-Trejo D, Llobet R, Martínez I, Pino MN, Martínez-Cortés M, Pérez-Gómez B, Lope V, García-Pérez J. Mammographic density in the environs of multiple industrial sources. Sci Total Environ. 2023 Jun 10;876:162768.

PUBMED DOI

The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data

Fernández-Navarro P, López-Nieva P, Piñeiro-Yañez E, Carreño-Tarragona G, Martinez-López J, Sánchez Pérez R, Aroca Á, Al-Shahrour F, Cobos-Fernández MÁ, Fernández-Piqueras J. The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data. BMC Cancer. 2019 Oct 26;19(1):1005.

PUBMED DOI

Are European HIV cohort data within EuroCoord representative of the diagnosed HIV population?

Vourli G, Pharris A, Cazein F, Costagliola D, Dabis F, Del Amo J, Delpech V, Díaz A, Girardi E, Gourlay A, Gunsenheimer-Bartmeyer B, Hernando V, Nikolopoulos G, Porter K, Rosińska M, Sabin C, Suligoi B, Supervie V, Wit F, Touloumi G. Are European HIV cohort data within EuroCoord representative of the diagnosed HIV population?. AIDS. 2018 Oct 4

PUBMED DOI

Health-related quality of life in people with HIV from the multicentre CoRIS cohort in Spain: Associated factors and short-term changes over time.

Izquierdo R, Suárez-García I, Marco-Sánchez C, Pérez-Latorre L, Riera M, Cano J, Viladés C, Reus S, Olalla J, González-Ruano P, Orviz E, Díaz A, Moreno S, Jarrín I; CoRIS cohort. HIV Med. 2025 Jan 21.

PUBMED DOI

Increasing trends in hepatitis E hospitalisations in Spain, 1997 to 2019. Euro Surveill. 2024;29(43):pii=2400118.

Guerrero-Vadillo María, Peñuelas Marina, Carmona Rocío, León-Gómez Inmaculada, Varela Carmen.

DOI

Effectiveness of XBB.1.5 Monovalent COVID-19 Vaccines During a Period of XBB.1.5 Dominance in EU/EEA Countries, October to November 2023: A VEBIS-EHR Network Study.

Monge S, Humphreys J, Nicolay N, Braeye T, Van Evercooren I, Holm Hansen C, et al. Influenza Other Respir Viruses. 2024 Apr;18(4):e13292.

PUBMED DOI

Validation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q).

Weintraub D, Chaudhuri KR, Schrag A, Martinez-Martin P, Rizos A, Mamikonyan E, Gallagher J, Schoen I, Staunton J, Fernandes MP, Rodriguez-Blazquez C. Validation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q). Mov Disord. 2025 Jun;40(6):1037-1046.

PUBMED DOI

Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence.

Ojeda Sánchez C, García-Pérez J, Gómez-Barroso D, Domínguez-Castillo A, Pardo Romaguera E, Cañete A, Ortega-García JA, Ramis R. Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence. Int J Environ Res Public Health. 2023 Jan 31;20(3):2506.

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The impact of taxing sugar-sweetened beverages on diabetes: a critical review.

Peñalvo JL. The impact of taxing sugar-sweetened beverages on diabetes: a critical review. Diabetologia. 2024 Mar;67(3):420-429.

PUBMED DOI

Impact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders.

López-Cuadrado T, Ortiz C, Ayuso-Álvarez A, Galán I. Impact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders. J Psychiatr Res. 2024 Jan;169:292-297.

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How patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study.

Romay-Barja M, Pascual-Carrasco M, De Tena-Dávila MJ, Falcón M, Rodriguez-Blazquez C, Forjaz MJ, Ayala A, Molina-de la Fuente I, Burgos A, Muñoz A, Benito A. How patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study. BMJ Open. 2021 May 20;11(5):e048702.

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Multicohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach

Domingo-Relloso A, Riffo-Campos AL, Zhao N, Ayala G, Haack K, Manterola C, Rhoades DA, Umans JG, Fallin MD, Herreros-Martinez M, Pollan M, Boerwinkle E, Platz EA, Jones MR, Bressler J, Joehanes R, Ryan CP, Gonzalez JR, Levy D, Belsky DW, Cole SA, Michaud DS, Navas-Acien A, Tellez-Plaza M. Multicohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach. JACC CardioOncol. 2024 Sep 10;6(5):731-742.

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Coordinated public health actions following the identification of a measles case arriving on an international flight, Spain: December 2022-January 2023.

López-Perea N et al. Travel Med Infect Dis, 2024.

DOI

Trends in mortality from cutaneous malignant melanoma in Spain (1982-2016): sex-specific age-cohort-period effects

Gutiérrez-González E, López-Abente G, Aragonés N, Pollán M, Pastor-Barriuso R, Sánchez MJ, Pérez-Gómez B. Trends in mortality from cutaneous malignant melanoma in Spain (1982-2016): sex-specific age-cohort-period effects. J Eur Acad Dermatol Venereol. 2019 Aug;33(8):1522-1528.

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Intake of fruit, vegetables and pulses, and all-cause, cardiovascular and cancer mortality: Results from a population-based prospective study

Martínez-Castañeiras P, Ortiz C, Fernandez de Larrea-Baz N, Lope V, Sánchez-Gordón G, Ruiz-Moreno E, Alonso I, Garcia-Esquinas E, Pérez-Gómez B, Pastor-Barriuso R, Galán I, Castelló A. Intake of fruit, vegetables and pulses, and all-cause, cardiovascular and cancer mortality: Results from a population-based prospective study. Public Health. 2025 Feb;239:169-178.

PUBMED DOI

Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults

García-Esquinas E, Ortolá R, Martínez-Gómez D, Damián J, Prina M, Rodríguez-Artalejo F, Pastor-Barriuso R. Causal effects of physical activity and sedentary behaviour on health deficits accumulation in older adults. Int J Epidemiol. 2021 Jul 9;50(3):852-865.

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Risk of gastric cancer in the environs of industrial facilities in the MCC-Spain study.

García-Pérez J, Lope V, Fernández de Larrea-Baz N, Molina AJ, Tardón A, Alguacil J, Pérez-Gómez B, Moreno V, Guevara M, Castaño-Vinyals G, Jiménez-Moleón JJ, Gómez-Acebo I, Molina-Barceló A, Martín V, Kogevinas M, Pollán M, Aragonés N. Risk of gastric cancer in the environs of industrial facilities in the MCC-Spain study. Environ Pollut. 2021 Jun 1;278:116854.

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Awareness, knowledge, use, willingness to use and need of Pre-Exposure Prophylaxis (PrEP) during World Gay Pride 2017

Iniesta C, Álvarez-Del Arco D, García-Sousa LM, Alejos B, Díaz A, Sanz N, Garrido J, Meulbroek M, Pujol F, Moreno S, Fuster-Ruiz de Apocada MJ, Coll P, Antela A, Del Romero J, Ayerdi O, Riera M, Hernández J, Del Amo J. Awareness, knowledge, use, willingness to use and need of Pre-Exposure Prophylaxis (PrEP) during World Gay Pride 2017. Plos One. 2018; 13(10):e0204738

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Trends in new HIV diagnoses and factors contributing to late diagnosis among migrant populations in EU/EEA countries, 2014 to 2023.

Reyes-Urueña J, Stoppa G, Pizzolato F, van der Werf MJ, Deogan C, Cabral-Veríssimo V, Cortes-Martins H, Deblonde J, Diaz A, Hernando V, Milunka-Kojic E, Mossong J, O’Donnell K, Op de Coul E, Tsiara C, van Leest L, Van Beckhoven D, Wessman M, Whittaker R, the EU/EEA HIV network. Euro Surveill. 2024; 29(48): pii=2400759.

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Markers of inflammation and immune dysfunction and non-AIDS cancer risk in adults with HIV. v

Izquierdo R, Vallejo A, Suárez-García I, Martín-Hondarza A, Gutierrez F, Perez-Molina JA, García DV, Macías J, Rivero A, Olalla J, Montero-Alonso M, Asensi V, Moreno S, Jarrín I, Rava M; CoRIS cohort. J Acquir Immune Defic Syndr. 2025 Apr 7.

PUBMED DOI

Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019)

13. Guerrero-Vadillo M, Peñuelas Martínez M, Varela Martínez C. Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019). BES [Internet]. 24 de enero de 2022 ;29(2). Disponible en: //revista.isciii.es/index.php/bes/article/view/1124

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Trends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009

Diez M, Bleda MJ, Varela JR, Ordoñana J, Azpiri MA, Vall M, Santos C, Viloria L, de Armas C, Urena JM, Trullen J, Pueyo I, Martinez B, Puerta T, Vera M, Sanz I, Junquera ML, Landa MC, Martinez E, Camara MM, Belda J, Bru FJ, Diaz A; EPI-VIH Study Group. Trends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009. Euro Surveill. 2014;19 (47):20971.

PUBMED DOI

COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA.1/BA.2 lineages among adults and adolescents in a multicentre primary care study, Europe, December 2021 to June 2022.

Lanièce Delaunay C, Martínez-Baz I, Sève N, Domegan L, Mazagatos C, Buda S, et al. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2024 Mar;29(13).

PUBMED DOI

Rasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study.

Forjaz, M.J., Ayala, A., Schutte, L., Wissing MP, Temane QM, Campbell TCH, Carroll MTC. Rasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study. Soc Indic Res 179, 47–66 (2025).

DOI

Cardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin.

Sagastume D, Siero I, Mertens E, Peñalvo JL. Cardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin. Curr Cardiol Rep. 2022 Dec;24(12):1799-1810.

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Clinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study

López-Cuadrado T, Szmulewicz A, Öngür D, Martínez-Alés G. Clinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study. Gen Hosp Psychiatry. 2023 Sep-Oct;84:234-240.

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List of staff

Información adicional

The group dedicates its activities to public health research in the field of diseases for which vaccines are included in the common immunization schedule. To do so, it uses information collected from the National Epidemiological Surveillance Network (RENAVE), information from other systems and registries, and specifically designed studies.

The research lines and projects are developed in collaboration with the National Center for Microbiology (CNM-ISCIII), the Ministry of Health, the Autonomous Communities, the European Centre for the Prevention and Control of Communicable Diseases (ECDC), and other international consortia and research groups working in the field of vaccine-preventable diseases.

The group also conducts collaborative research within CIBERESP, within Group 32, and within the Program for the Prevention, Surveillance, and Control of Communicable Diseases (PREVICET).

 

Mission

To improve knowledge about communicable diseases prevented by vaccination through epidemiological surveillance and research.

The objective is to provide quality information to evaluate the impact and effectiveness of the vaccination programs included in the Common Childhood Immunization Schedule of the National Health System. Of particular importance is documenting the process of polio eradication and the elimination of measles and rubella in Spain, thus contributing to achieving the goals set by WHO Europe.

The research lines are developed in the field of public health research and study the impact that vaccination programs have on the epidemiology of diseases.