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Investigación
Epidemiología de enfermedades cardiovasculares y metabólicas
Líneas de investigación
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Enfermedades Prevenibles por Vacunación
- Vigilancia en la fase avanzada de erradicación de la poliomielitis. Vigilancia de la Parálisis Flácida Aguda.
- Vigilancia y epidemiología del sarampión y rubeola en fase de post-eliminación en España. Evaluación de nuevas herramientas en la vigilancia genómica del sarampión.
- Vigilancia epidemiológica y virológica de la parotiditis en España: patrones de circulación del virus de la parotiditis en el contexto de brotes epidémicos.
- Estudio de la reemergencia de tosferina en España después de la pandemia por COVID-19. Impacto de la vacunación de las gestantes en la gravedad de la tosferina en lactantes.
- Variaciones en la epidemiología de la varicela y del herpes zóster tras la inclusión de la vacunación en el calendario.
- Análisis de la evolución de los serotipos que causan la enfermedad neumocócica invasiva (ENI) en la actualidad, para adaptar las estrategias de prevención y control de la enfermedad
- Análisis comparativo de las tasas de incidencia de enfermedad meningocócica invasiva en las distintas Comunidades Autónomas. Evaluación del sistema de vigilancia de la enfermedad meningocócica invasiva.
- Vigilancia de los casos de enfermedad invasiva por Haemophilus influenzae tipo b (Hib) tras el cambio de pauta de vacunación en el programa de vacunación aprobado por el Sistema Interterritorial del Sistema Nacional de Salud en 2017. Análisis del incremento de casos de Hi capsulares (distintos a Hib) y no capsulares de los últimos años
Publicaciones destacadas
Scoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public health measures
Angelos Amditis, Spyridon Athanasiadis, Szava J. Bansaghi, Despoina A. Bygvraa, Stefanos Chatzimichelakis, Reuben D’Souza, Dimitra Dionysiou, Maria Guerrero-Vadillo, Giorgio Guzzetta, Volker Harth, Jan Heidrich, Jörn Klein, Jürgen F. Kolb, Prashant Kumar, Pierfrancesco Lepore, Sergiu Lupu, Valentina Marziano, Johannes Neumann, Symeon Nikolaou, Filip Nistor, Eleftherios Ouzounoglou, Vassilis Papataxiarhis, Marina Peñuelas, Patrizio Pezzotti, Catalin Popa, Raphael Rataj, Smaragda Reppa, Flavia Riccardo, Hannu Salmela, Niko Siilin, Konstantinos Theofilis, Constantinos Tsibanis, Carmen Varela, Nikolaos P. Ventikos, Georgios Vosinakis, Goran Vukelić, Christine Zädow & Vassilios Zagkas.
PUBMED DOIEstimated Impact of Nirsevimab on the Incidence of Respiratory Syncytial Virus Infections Requiring Hospital Admission in Children < 1 Year, Weeks 40, 2023, to 8, 2024, Spain.
Mazagatos C, Mendioroz J, Rumayor MB, Gallardo García V, Álvarez Río V, Cebollada Gracia AD, et al. Influenza Other Respir Viruses. 2024 May;18(5):e13294.
PUBMED DOIAssociation between type of alcoholic beverage and all-cause mortality. A population-based prospective study.
Fontán-Vela J, Ortiz C, López-Cuadrado T, Téllez-Plaza M, García-Esquinas E, Ortolá R, Rodríguez-Artalejo F, Galán I. Association between type of alcoholic beverage and all-cause mortality. A population-based prospective study. Public Health. 2025 Jun;243:105728.
PUBMED DOIImpact of a community-based multisectoral intervention on the health of individuals with parkinson's disease and their family caregivers.
Calzada García M, Ayala A, Navarta Sánchez MV, Palmar Santos AM, Portillo MC, González García B, Carabajal Pendón E, López Manzanares L, Pedraz Marcos A. Impacto de una intervención multisectorial comunitaria en la salud de las personas con enfermedad de Parkinson y sus familiares cuidadores [Impact of a community-based multisectoral intervention on the health of individuals with parkinson's disease and their family caregivers]. Semergen. 2026 Mar;52(2):102694. Spanish.
PUBMED DOIEnfermedad meningocócica invasiva en España en 2024.
Martín-Sánchez A, del Águila Mejía J, Acosta-Gutiérrez M, Soler-Soneira M, Cano-Portero R, Masa-Calles J. Boletín Epidemiológico Semanal. 2025;33(3):135-152.
DOITwo-season effectiveness of a single nirsevimab dose against RSV hospitalisation in healthy term-born infants: a population-based case–control study, Spain, October 2023 to March 2025.
Núñez O, Juaneda J, (...), Monge S, Pastor-Barriuso R., the Nirsevimab Effectiveness Study Collaborators. Two-season effectiveness of a single nirsevimab dose against RSV hospitalisation in healthy term-born infants: a population-based case–control study, Spain, October 2023 to March 2025. Euro Surveill. 2026;31(9):pii=2500593.
DOIBreastfeeding knowledge, attitudes and practices of HIV-positive women in Africa: a systematic review
Cuenca-Viñas N, Sánchez-Marqués R, Benito A, Romay-Barja M. Breastfeeding knowledge, attitudes and practices of HIV-positive women in Africa: a systematic review. Int Breastfeed J. 2025 Sep 29;20(1):74.
PUBMED DOIAssociation of depressive symptoms with all-cause, cardiovascular, and cancer mortality: A population-based study in Spain.
López-Cuadrado T, Ortiz C, Pastor-Barriuso R, Galán I. Association of depressive symptoms with all-cause, cardiovascular, and cancer mortality: A population-based study in Spain. Span J Psychiatry Ment Health. 2026 Mar 3:S2950-2853(26)00015-3.
PUBMED DOIIncreased trends in reported sexually transmitted infections according to age groups and sex in Spain, 2016–2022.
Hernando V, Lorusso N, Montaño C, Boone A LD, Garí A, Perez G, Viloria L, Morales R, Marcos H, Casabona J, Bellmut P, Vicente S, Pérez O, Miguel A, Barranco-Boada MI, Castilla J, Latasa P, Martínez E, Rivas AI, Castrillejo D, Villegas-Moreno T, Simón L, Diaz A, and STIs Study Group of National Epidemiological Surveillance Network. Infect Dis (Lond). 2025 Mar;57(3):247-255.
PUBMED DOIFirst report in two decades of ciguatera fish poisoning linked to small-sized fish consumption in the Canary Islands
Ana Hernández-Aceituno, Isabel Falcón García, Álvaro Torres Lana, Francisco M Martín León, María José Ramos-Sosa, Andres Sanchez-Henao, Carmen Varela Martínez, M Iluminada Negrín Díaz, Eneko Larumbe-Zabala, Jesús Ulises Cabrera García, Minerva Matos Cruz, Miguel Ángel González Cortes, María Fernanda Marín Barragán, Fernando Real Valcárcel.
PUBMED DOIHarmonization of alcohol use data and mortality across a multi-national HIV cohort collaboration.
Ingle SM, Trickey A, Lankina A, McGinnis KA, Justice A, Cavassini M, d' Arminio Monforte A, van Sighem A, Gill MJ, Crane HM, Obel N, Jarrin I, Wallner E, Guest J, Silverberg MJ, Vourli G, Wittkop L, Sterling TR, Satre DD, Burkholder GA, Costagliola D, Sterne JAC. Alcohol Clin Exp Res (Hoboken). 2025 Jan 8. doi: 10.1111/acer.15522. Epub ahead of print.
PUBMED DOIEpidemiología y carga de enfermedad por VRS en España. SiVIRA, temporadas 2021-22 y 2022-23.
Puma Olguin TC, Mazagatos C, Galindo-Carretero S, Vega-Piris L, Lozano-Álvarez M, Pérez-Gimeno G, et al. BES. 2024 May 6; 32(1):21-35.
DOIIndependent and combined effect of sitting time and physical activity on all-cause mortality in Spain: a population-based prospective study.
Granero-Melcón B, de la Cámara MÁ, Ortiz C, Martínez-Portillo A, Neira-León M, Galán I. Independent and combined effect of sitting time and physical activity on all-cause mortality in Spain: a population-based prospective study. Eur J Public Health. 2025 Jun 1;35(3):548-554.
PUBMED DOIDeterminants of cesarean section rates: A cross-sectional study of 4.9 million deliveries over 10 years.
Alonso-Colón M, Pérez-Gómez B, Ramis R. Determinants of cesarean section rates: A cross-sectional study of 4.9 million deliveries over 10 years. Eur J Obstet Gynecol Reprod Biol. 2025 Aug;312:114527.
PUBMED DOIInfants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season.
Pastor-Barriuso R, Núñez O, Monge S; Nirsevimab Effectiveness Study Collaborators. Infants needed to immunise with nirsevimab to prevent one RSV hospitalisation, Spain, 2023/24 season. Euro Surveill. 2025 Feb;30(6):2500040.
PUBMED DOIVaricela en España, 1997-2023. Análisis preliminar del impacto de la vacunación universal en la infancia.
Torres de Mier MV, Masa-Calles J. Boletín Epidemiológico Semanal. 2025;33(1):45-57.
DOIThe relevance of WHO behavioural health insights
Romay Barja M, Bilos IB, Bratu EC, Falcón M, Forjaz MJ, Nagyova I, Niskanovic J, Osiptchik S, Rodríguez-Blázquez C, Sanders J, Takhirova F, de Arriga MT, Van der Biest L. The relevance of WHO behavioural health insights. Lancet. 2025 Jun 7;405(10494):2045-2046
PUBMED DOITrends of non-lethal intentional self-harm and suicide in Spain 2018-2023: a nationwide registry-based study
López-Cuadrado T, Mortier P, Alonso J, Martínez-Alés G. Trends of non-lethal intentional self-harm and suicide in Spain 2018-2023: a nationwide registry-based study. Lancet Reg Health Eur. 2025 Sep 27;58:101467.
PUBMED DOIExploring the effect of clinical case definitions on influenza vaccine effectiveness estimation at primary care level: Results from the end-of-season 2022-23 VEBIS multicentre study in Europe.
Maurel M, Mazagatos C, Goerlitz L, Oroszi B, Hooiveld M, Machado A, et al. Vaccine. 2024 Jun 11;42(16):3547–54.
PUBMED DOIMarked increase in cryptosporidiosis cases, Spain, 2023. Euro Surveill. 2024;29(28):2300733.
Peñuelas Martínez M, Carmena D, Guzmán Herrador BR, et al.
DOIQuality of life of informal caregivers 50 years old and older in Spain by household living status: a descriptive study.
Bernal-Alonso A, Rodríguez-Blázquez C, Fernández-Carro C, Ayala A, Calderón-Larrañaga A, Forjaz MJ. Quality of life of informal caregivers 50 years old and older in Spain by household living status: a descriptive study. Sci Rep. 2025 Jul 1;15(1):21121.
PUBMED DOIUrban environmental noise and depression causal pathway: Potential role of chronic conditions as mediator.
Sanz Olea E, Hernández JL, Artíñano B, Briz V, Karakitsios S, Sarigiannis D, García Dos Santos S, Nuñez-Corcuera B, Ramis R. Urban environmental noise and depression causal pathway: Potential role of chronic conditions as mediator. PLoS One. 2025 May 7;20(5):e0322874.
PUBMED DOINon-genetic and genetic determinants of serum selenium and selenium species in the Aragon Workers Health Study.
Rodriguez-Hernandez Z, Paredes-Douton A, Galvez-Fernandez M, Grau-Perez M, Sotos-Prieto M, Rentero-Garrido P, Gonzalez-Estecha M, Llorente-Ballesteros MT, Gomez-Ariza JL, Callejon-Leblic B, Fernandez-Navarro P, Laclaustra M, Cenarro A, Civeira F, Glabonjat RA, Monleon D, Pastor-Barriuso R, Moreno-Franco B, Garcia-Barrera T, Tellez-Plaza M. Non-genetic and genetic determinants of serum selenium and selenium species in the Aragon Workers Health Study. Free Radic Biol Med. 2025 Jun;233:365-377.
PUBMED DOIEffectiveness of catch-up and at-birth nirsevimab immunisation against RSV hospital admission in the first year of life: a population-based case-control study, Spain, 2023/24 season
Núñez O, Olmedo C, (…), Pastor-Barriuso R, Monge S; Nirsevimab Effectiveness Study Collaborators. Effectiveness of catch-up and at-birth nirsevimab immunisation against RSV hospital admission in the first year of life: a population-based case-control study, Spain, 2023/24 season. Euro Surveill. 2025 Feb;30(5):2400596. doi: 10.2807/1560-7917.ES.2025.30.5.2400596. Erratum in: Euro Surveill. 2025 Apr;30(13).
PUBMED DOIEnfermedad Neumocócica Invasiva en España en 2023.
Soler Soneira M, Del-Águila-Mejía J, Acosta-Gutiérrez M, Sastre-García M, Amillategui- Dos-Santos R, Cano Portero R. BES [Internet]. 29 de julio de 2024 [citado 28 de agosto de 2024];32(2):74-93.
DOICharacteristics of adults who reported not having had COVID-19 in Spain after the first two years of the pandemic and associated factors.
Beca-Martínez MT, Ayala A, Falcón-Romero M, Rodríguez-Blázquez C, Benito-Llanes A, Forjaz MJ, Romay-Barja M. Characteristics of adults who reported not having had COVID-19 in Spain after the first two years of the pandemic and associated factors. J Infect Public Health. 2024 Mar;17(3):435-442.
PUBMED DOISIPrEP: a tool to monitor HIV pre-exposure prophylaxis in Spain.
Enferm Infecc Microbiol Clin (Engl Ed). 2025; 43(8):515-522. Iniesta C, Hernando V, Jarrín I, Pérez de la Cámara S, de la Torre J, Villanueva V, Mayorga MI, Belda J, Soteras M, Torres Lana A, Echevarria A, Monteagudo O, Marcos H, Ben Cheikh W, Portocarrero-Núñez JA, Álvarez-del Arco D, Diaz A, del Amo J y SIPrEP Working Group.
PUBMED DOIBrotes de transmisión alimentaria e hídrica en España, 2018-2022. BES [Internet]. 29 de julio de 2024 [citado 31 de octubre de 2024];32(2):61-73.
Sanz-Olea E, Peñuelas M, Guerrero-Vadillo M, Sastre-García M, Díaz O, Cano-Portero R, et al.
DOIShould we measure quality of life among people with HIV? A multicentre survey of physicians' opinions in Spain.
Izquierdo R, Suárez-García I, Gómez-García T, Marco-Sánchez C, Puente-Ferreiro J, Moreno C, Diaz A, Cabello-Clotet N, Vinuesa D, Blanco JL, Melús E, Gómez-Ayerbe C, Olalla J, Riera M, Bernardino JI, de López Bernaldo de Quirós JC, Moreno S, Jarrín I; CoRIS cohort.
PUBMED DOIComparative severity of COVID-19 cases caused by Alpha, Delta or Omicron SARS-CoV-2 variants and its association with vaccination.
Varea-Jiménez E, Aznar Cano E, Vega-Piris L, Martínez Sánchez EV, Mazagatos C, García San Miguel Rodríguez-Alarcón L, et al. Enfermedades Infecc Microbiol Clin Engl Ed. 2024 Apr;42(4):187–94.
PUBMED DOIEuropean HIV continuum of care working group. The HIV continuum of care in European Union countries in 2013: data and challenges
Gourlay A, Noori T, Pharris A, Axelsson M, Costagliola D, Cowan S, Croxford S, d'Arminio Monforte A, Del Amo J, Delpech V, Díaz A, Girardi E, Gunsenheimer-Bartmeyer B, Hernando V, Jose S, Leierer G, Nikolopoulos G, Obel N, Op de Coul E, Paraskeva D, Reiss P, Sabin C, Sasse A, Schmid D, Sonnerborg A, Spina A, Suligoi B, Supervie V, Touloumi G, Van Beckhoven D, van Sighem A, Vourli G, Zangerle R, Porter K; European HIV continuum of care working group. The HIV continuum of care in European Union countries in 2013: data and challenges. Clin Infect Dis. 2017; 64(12)1644-56
PUBMED DOIChanges in mental health diagnosis and healthcare use in seven European countries before and during the COVID-19 pandemic (2017-21).
Rodríguez-Blazquez C, Aldridge SJ, Bernal-Delgado E, Calomfirescu C, Dolanski-Aghamanoukjan L, Estupiñán-Romero F, Gissler M, Beate G, Idavain J, Larose TL, Lyons RA, Mathis-Edenhofer S, Miller K, Misiņš J, Radulescu S, Rätsep M, Sagerschnig S, Sandu P, Šitcs J, Pavlovska Z, Thißen M, Tolonen H, Garriga C, Forjaz MJ. Changes in mental health diagnosis and healthcare use in seven European countries before and during the COVID-19 pandemic (2017-21). Eur J Public Health. 2025 Jun 1;35(3):484-490.
PUBMED DOIAssociation of miR-126-3p, miR-1260b and miR-374a-5p with the incidence of heart failure in a population-based cohort: the Hortega Follow-Up Study.
Grau-Perez M, Martinez-Arroyo O, Rubia-Martinez M, Flores-Chova A, Rodriguez-Hernandez Z, Fernández-Navarro P, Gonzalez-Neira A, Alonso MR, Pita G, Pineda S, Martin-Escudero JC, Ortega A, Redon J, Tellez-Plaza M, Cortes R. Association of miR-126-3p, miR-1260b and miR-374a-5p with the incidence of heart failure in a population-based cohort: the Hortega Follow-Up Study. Eur J Intern Med. 2025 May;135:118-125.
PUBMED DOIVolume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study.
Galán I, Fontán J, Ortiz C, López-Cuadrado T, Téllez-Plaza M, García-Esquinas E. Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study. Addict Behav. 2024 Nov;158:108108.
PUBMED DOIA growing disconnection from nature. Urgent call to action for a nature prescription global health alliance.
Ortega-García JA, Martínez-Gómez C, Bach A, Benitez-Rodríguez L, Ramis R; en representación de la Alianza GRSIA. A growing disconnection from nature. Urgent call to action for a nature prescription global health alliance. An Pediatr (Engl Ed). 2024 Jun;100(6):e10-e12.
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Carmen Varela
Científico titular OPIs
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María Guerrero
Técnico superior facultativo y especialista
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Marina Peñuelas
Técnico superior facultativo y especialista
ORCID code: null
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Teresa López Cuadrado
Técnico superior especialista
ORCID code: null
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Sara Gayol Suárez
Técnico especializado
ORCID code: null
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María Carmen Rodríguez Blázquez
Técnico especializado
ORCID code: null
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Susana Villarrubia Enseñat
Jefa de Sección
ORCID code: null
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Rebeca Ramis Prieto
Científica Titular
ORCID code: null
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Marina Pollán Santamaría
Directora CNE, Jefa de Unidad, prof. investigación
ORCID code: null
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Roberto Pastor-Barriuso
Científico Titular
ORCID code: null
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Cristina Ortíz
Beca pre-doctoral AESI-PFIS
ORCID code: null
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Olivier Nuñez
Técnico Especializado de OPI
ORCID code: null
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Cristina Moreno Prieto
Titulado superior de actividades técnicas y profesionales
ORCID code: null
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Carmen Martín Mesonero
Especialista I+D+I
ORCID code: null
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List of staff