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Investigación
Epidemiología de enfermedades cardiovasculares y metabólicas
Líneas de investigación
Content with Investigacion .
Enfermedades Prevenibles por Vacunación
- Vigilancia en la fase avanzada de erradicación de la poliomielitis. Vigilancia de la Parálisis Flácida Aguda.
- Vigilancia y epidemiología del sarampión y rubeola en fase de post-eliminación en España. Evaluación de nuevas herramientas en la vigilancia genómica del sarampión.
- Vigilancia epidemiológica y virológica de la parotiditis en España: patrones de circulación del virus de la parotiditis en el contexto de brotes epidémicos.
- Estudio de la reemergencia de tosferina en España después de la pandemia por COVID-19. Impacto de la vacunación de las gestantes en la gravedad de la tosferina en lactantes.
- Variaciones en la epidemiología de la varicela y del herpes zóster tras la inclusión de la vacunación en el calendario.
- Análisis de la evolución de los serotipos que causan la enfermedad neumocócica invasiva (ENI) en la actualidad, para adaptar las estrategias de prevención y control de la enfermedad
- Análisis comparativo de las tasas de incidencia de enfermedad meningocócica invasiva en las distintas Comunidades Autónomas. Evaluación del sistema de vigilancia de la enfermedad meningocócica invasiva.
- Vigilancia de los casos de enfermedad invasiva por Haemophilus influenzae tipo b (Hib) tras el cambio de pauta de vacunación en el programa de vacunación aprobado por el Sistema Interterritorial del Sistema Nacional de Salud en 2017. Análisis del incremento de casos de Hi capsulares (distintos a Hib) y no capsulares de los últimos años
Publicaciones destacadas
Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network.
Rose AMC, Pozo F, Martínez-Baz I, Mazagatos C, Bossuyt N, Cauchi JP, et al. Influenza Other Respir Viruses. 2024 Feb;18(2):e13255.
PUBMED DOIThe Hospital Survey Study Group C. A low-cost, sustainable, second generation system for surveillance of people living with HIV in Spain: 10-year trends in behavioural and clinical indicators, 2002 to 2011
Diez M, Diaz A, Garriga C, Pons M, Ten A, Marcos H, Gutierrez G, Moreno S, Gonzalez-Garcia J, Barrios A, Arponen S, Garcia M, Royo M, Toledo J, Gonzalez G, Aranguren R, Izquierdo A, Viloria LJ, Elizalde L, Martinez E, Castrillejo D, Lopez I, Redondo C, Cano A, The Hospital Survey Study Group C. A low-cost, sustainable, second generation system for surveillance of people living with HIV in Spain: 10-year trends in behavioural and clinical indicators, 2002 to 2011. Euro Surveill. 2014; 19(20). pii: 20805
PUBMED DOIOmics feature selection with the extended SIS R package: identification of a body mass index epigenetic multimarker in the Strong Heart Study
Domingo-Relloso A, Feng Y, Rodriguez-Hernandez Z, Haack K, Cole SA, Navas-Acien A, Tellez-Plaza M, Bermudez JD. Omics feature selection with the extended SIS R package: identification of a body mass index epigenetic multimarker in the Strong Heart Study. Am J Epidemiol. 2024 Jul 8;193(7):1010-1018.
PUBMED DOIThe effectiveness of lifestyle interventions on type 2 diabetes and gestational diabetes incidence and cardiometabolic outcomes: A systematic review and meta-analysis of evidence from low- and middle-income countries.
Sagastume D, Siero I, Mertens E, Cottam J, Colizzi C, Peñalvo JL. The effectiveness of lifestyle interventions on type 2 diabetes and gestational diabetes incidence and cardiometabolic outcomes: A systematic review and meta-analysis of evidence from low- and middle-income countries. EClinicalMedicine. 2022 Sep 9;53:101650.
PUBMED DOIIdentification of methodological issues regarding direct impact indicators of COVID-19: a rapid scoping review on morbidity, severity and mortality.
Garriga C, Valero-Gaspar T, Rodriguez-Blazquez C, Diaz A, Bezzegh P, Daňková Š, Unim B, Palmieri L, Thiβen M, Pentz R, Cilović-Lagarija Š, Jogunčić A, Feteira-Santos R, Vuković J, Idavain J, Curta A, Sandu P, Vinko M, Forjaz MJ. Identification of methodological issues regarding direct impact indicators of COVID-19: a rapid scoping review on morbidity, severity and mortality. Eur J Public Health. 2024 Jul 1;34(Supplement_1):i3-i10.
PUBMED DOIUtility of MF-non coding region for measles molecular surveillance during post-elimination phase, Spain, 2017-2020.
Jacqueline C, Gavilán AM, López-Perea N, Penedos AR, Masa-Calles J, Echevarría JE, Fernández-García A; MMR Study Group. Front Microbiol. 2023 May 22;14:1143933.
DOIHepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022
9. Vidal A.R., Vaughan A., Innocenti F., Colombe S., Nerlander L., Rachwal N., Ciancio B.C., Mougkou A., Carvalho C., Delgado E., Mook P., De Muylder G., Peeters M., Tenev T., Golkocheva-Markova E., Jensen V.V.S., Koch A., Figoni J., Brouard C., Nikolopoulou G., Zisouli A., Murphy N., Broderick A., Goldberg L., Rich R., Sagie L.H., Tosti M.E., Suligoi B., Joosten R., Pijnacker R., Fjeldheim I., Heen E., Stȩpień M., Polański P., Marinho R.T., Martins J.V., Varela C., Avellón A., Andersson E., Mörk M.J., Mandal S., Watson C., Coughlan L., Chand M., Neill C., Bradley D.T., Li K., O'Leary M., McInnes N., Williams C.J., Moore C., Gjini A., Duffell E., Pebody R.. Hepatitis of unknown aetiology in children – epidemiological overview of cases reported in Europe, 1 January to 16 June 2022. Euro Surveill. 2022;27(31):pii=2200483.
PUBMED DOILong-term effectiveness and tolerability of dolutegravir/lamivudine in treatment-naive people with HIV: an analysis of a multicentre cohort at 96 weeks.
Suárez-García I, Alejos B, Moreno C, Martín Torres J, Masiá M, García-Fraile LJ, Riera M, Dalmau D, Rodríguez-Rosado R, Muga R, Moreno S, Jarrín I; CoRIS cohort. J Antimicrob Chemother. 2025 Mar 3;80(3):682-691.
PUBMED DOIEffects of region of birth, educational level and age on late presentation among men who have sex with men newly diagnosed with HIV in a network of STI/HIV counselling and testing clinics in Spain
Diaz A, del Romero J, Rodriguez C, Alastrue I, Belda J, Bru FJ, Cámara MM, Junquera ML, Sanz I, Viloria LJ, Gil L, Martínez E, Gual F, Landa MC, Pueyo I, Ureña JM, Martínez B, Varela JA, Polo A, Azpiri MA, Diez M, for the EPI-VIH Study Group. Effects of region of birth, educational level and age on late presentation among men who have sex with men newly diagnosed with HIV in a network of STI/HIV counselling and testing clinics in Spain. Euro Surveill. 2015;20(14):pii=21088.
PUBMED DOIUrban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid.
Ojeda Sánchez C, Segú-Tell J, Gomez-Barroso D, Pardo Romaguera E, Ortega-García JA, Ramis R. Urban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid. Environ Res. 2021 Nov;202:111723.
PUBMED DOIVigilancia epidemiológica y virológica de la parotiditis en España, 2005-2022.
Horcas de Frutos A, López-Perea N, Fernández-García A, Gavilán AM, Echevarría JE, Olivares-Quintanar D, et al. BES [Internet]. 29 de septiembre de 2023, 31(3):139-65.
DOIInvestigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022
10. Larkin L., de la Gandara M.P., Hoban A., Pulford C., Silva N.J.-D., de Valk H., Browning L., Falkenhorst G., Simon S., Lachmann R., Dryselius R., Karamehmedovic N., Börjesson S., van Cauteren D., Laisnez V., Mattheus W., Pijnacker R., van den Beld M., Mossong J., Ragimbeau C., Vergison A., Brandal L.T., Lange H., Garvey P., Nielsen C.S., León S.H., Varela C., Chattaway M., Weill F.-X., Brown D., McKeown P. Investigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU/EEA and United Kingdom, February to April 2022. Euro Surveill2022;27(15):pii=2200314.
PUBMED DOIPregnancy in Women with HIV: Incidence and Outcomes over 19 Years in a Multi-Center Cohort in Spain.
Suárez-García I, Moreno C, Alejos B, Izquierdo R, Pérez de la Cámara S, Pardo OB, Arenzana CB, Pérez-Elías MJ, López TP, Imaz A, Curran A, Hernando V, Jarrín I; CoRIS cohort. AIDS Patient Care STDS. 2025 Oct;39(10):385-396.
PUBMED DOIAssessment of an outreach street-based HIV rapid testing programme as a strategy to promote early diagnosis: a comparison with two surveillance systems in Spain, 2008–2011
Belza MJ, Hoyos J, Fernández-Balbuena S, Diaz A, Bravo MJ, de la Fuente L, the Madrid HIV rapid testing group. Assessment of an outreach street-based HIV rapid testing programme as a strategy to promote early diagnosis: a comparison with two surveillance systems in Spain, 2008–2011. Euro Surveill. 2015;20(14):pii=21089
PUBMED DOIAssociation of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: The national health and nutrition examination survey 1999-2018.
Gonzalez-Martin R, Grau-Perez M, Sebastian-Leon P, Diaz-Gimeno P, Vidal C, Tellez-Plaza M, Dominguez F. Association of blood cadmium and lead levels with self-reported reproductive lifespan and pregnancy loss: The national health and nutrition examination survey 1999-2018. Environ Res. 2023 Sep 15;233:116514.
PUBMED DOIAn interregional measles outbreak in Spain with nosocomial transmission, November 2017 to July 2018.
Pampaka Despina, López-Perea Noemí, Fernández-García Aurora, Huertas-Zarco Isabel, Castellanos-Martínez Maite, Villatoro-Bongiorno Katja, Roig-Sena Javier, Torner Nuria, Mar Mosquera María, Echevarría Juan Emilio, Prats Joaquim Ferras, Masa-Calles Josefa. Euro Surveill. 2023;28(17):pii=2200634.
DOIVigilancia epidemiológica de Shigelosis en España, 2016-2021
12. Guerrero-Vadillo M, Peñuelas M, Herrera León S, Suarez Rodriguez B, Díaz A, Guzmán Herrador B, et al. Vigilancia epidemiológica de Shigelosis en España, 2016-2021. BES [Internet]. 21 de marzo de 2022;29(8):90-8. Disponible en: //revista.isciii.es/index.php/bes/article/view/1201
PUBMED DOITraffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.
Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero JC, Ramis R. Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study. Antioxidants (Basel). 2023 Dec 15;12(12):2122.
PUBMED DOI