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Investigación
Epidemiología de enfermedades cardiovasculares y metabólicas
Líneas de investigación
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Enfermedades Prevenibles por Vacunación
- Vigilancia en la fase avanzada de erradicación de la poliomielitis. Vigilancia de la Parálisis Flácida Aguda.
- Vigilancia y epidemiología del sarampión y rubeola en fase de post-eliminación en España. Evaluación de nuevas herramientas en la vigilancia genómica del sarampión.
- Vigilancia epidemiológica y virológica de la parotiditis en España: patrones de circulación del virus de la parotiditis en el contexto de brotes epidémicos.
- Estudio de la reemergencia de tosferina en España después de la pandemia por COVID-19. Impacto de la vacunación de las gestantes en la gravedad de la tosferina en lactantes.
- Variaciones en la epidemiología de la varicela y del herpes zóster tras la inclusión de la vacunación en el calendario.
- Análisis de la evolución de los serotipos que causan la enfermedad neumocócica invasiva (ENI) en la actualidad, para adaptar las estrategias de prevención y control de la enfermedad
- Análisis comparativo de las tasas de incidencia de enfermedad meningocócica invasiva en las distintas Comunidades Autónomas. Evaluación del sistema de vigilancia de la enfermedad meningocócica invasiva.
- Vigilancia de los casos de enfermedad invasiva por Haemophilus influenzae tipo b (Hib) tras el cambio de pauta de vacunación en el programa de vacunación aprobado por el Sistema Interterritorial del Sistema Nacional de Salud en 2017. Análisis del incremento de casos de Hi capsulares (distintos a Hib) y no capsulares de los últimos años
Publicaciones destacadas
Measles Among the Foreign-Born Population Residing in Spain, 2014–2022: Missed Opportunities for Vaccination.
Noemí López-Perea, Teresa López-Cuadrado, Aurora Fernández-García, Juan E. Echevarría, Josefa Masa-Calles. Vaccines, 2024
DOIAssociation Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic.
Agurto-Ramírez A, Pino-Rosón C, Ayala A, Falcón M, Rodríguez-Blázquez C, Forjaz MJ, Romay-Barja M. Association Between Pandemic Fatigue and Disease Knowledge, Attitudes, Concerns, and Vaccination Intention at Two Key Moments of the COVID-19 Pandemic. Int J Public Health. 2023 Sep 26;68:1606049.
PUBMED DOIRecent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study
López-Cuadrado T, Susser E, Martínez-Alés G. Recent trends in hospital admission due to bipolar disorder in 10-19-year-olds in Spain: A nationwide population-based study. Bipolar Disord. 2024 Dec;26(8):801-809.
PUBMED DOIAre European HIV cohort data within EuroCoord representative of the diagnosed HIV population?
Vourli G, Pharris A, Cazein F, Costagliola D, Dabis F, Del Amo J, Delpech V, Díaz A, Girardi E, Gourlay A, Gunsenheimer-Bartmeyer B, Hernando V, Nikolopoulos G, Porter K, Rosińska M, Sabin C, Suligoi B, Supervie V, Wit F, Touloumi G. Are European HIV cohort data within EuroCoord representative of the diagnosed HIV population?. AIDS. 2018 Oct 4
PUBMED DOIIncreasing trends in hepatitis E hospitalisations in Spain, 1997 to 2019. Euro Surveill. 2024;29(43):pii=2400118.
Guerrero-Vadillo María, Peñuelas Marina, Carmona Rocío, León-Gómez Inmaculada, Varela Carmen.
DOIHealth-related quality of life in people with HIV from the multicentre CoRIS cohort in Spain: Associated factors and short-term changes over time.
Izquierdo R, Suárez-García I, Marco-Sánchez C, Pérez-Latorre L, Riera M, Cano J, Viladés C, Reus S, Olalla J, González-Ruano P, Orviz E, Díaz A, Moreno S, Jarrín I; CoRIS cohort. HIV Med. 2025 Jan 21.
PUBMED DOIEffectiveness of XBB.1.5 Monovalent COVID-19 Vaccines During a Period of XBB.1.5 Dominance in EU/EEA Countries, October to November 2023: A VEBIS-EHR Network Study.
Monge S, Humphreys J, Nicolay N, Braeye T, Van Evercooren I, Holm Hansen C, et al. Influenza Other Respir Viruses. 2024 Apr;18(4):e13292.
PUBMED DOIDevelopment and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children.
Pons R, Pearson TS, Perez-Dueñas B, Garcia-Cazorla A, Kurian MA, Dalivigka Z, Zouvelou V, Outsika C, Kokkinou E, Sigatullina-Bondarenko M, Darling A, O'Callaghan MDM, Spaull R, Steel DBD, Salamou E, Forjaz MJ, Rodriguez-Blazquez C. Development and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children. Mov Disord. 2025 Aug;40(8):1669-1679.
PUBMED DOITraffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.
Sanchez-Rodriguez L, Galvez-Fernandez M, Rojas-Benedicto A, Domingo-Relloso A, Amigo N, Redon J, Monleon D, Saez G, Tellez-Plaza M, Martin-Escudero JC, Ramis R. Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study. Antioxidants (Basel). 2023 Dec 15;12(12):2122.
PUBMED DOIDifferential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults.
Rodriguez-Hernandez Z, Bel-Aguilar J, Moreno-Franco B, Grau-Perez M, Redon J, Gomez-Ariza JL, Garcia-Barrera T, Olmedo P, Gil F, Cenarro A, Civeira F, Puzo J, Casasnovas JA, Banegas JR, Sotos-Prieto M, Ortola R, Laclaustra M, Rodriguez-Artalejo F, Garcia-Esquinas E, Tellez-Plaza M, Pastor-Barriuso R. Differential association of selenium exposure with insulin resistance and β-cell function in middle age and older adults. Nutr Diabetes. 2025 Feb 13;15(1):5.
PUBMED DOIReduced pertussis disease severity in infants following the introduction of pertussis vaccination of pregnant women in Spain, 2015-2019.
Parisi A, Nuñez O, López-Perea N, Masa-Calles J. Vaccine. 2024 Mar 25:S0264-410X(24)00315-3.
DOIRisk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.
Ayuso-Álvarez A, Blasco Hernández T, Benito Llanes A. Percepción del riesgo de los profesionales sanitarios ante el primer caso de infección secundaria por ébola en España [Risk Perception among health professionals in the first case of secondary Ebola infection in Spain. Case study.]. Rev Esp Salud Publica. 2021 Sep 7;95:e202109136.
PUBMEDHospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study
Vázquez-Giraldo P, Muñoz-Sanjosé A, López-Cuadrado T. Hospital Admissions for Eating Disorders in Children and Adolescents in Spain: A Population-Based Study. Int J Eat Disord. 2024 Nov;57(11):2299-2305.
PUBMED DOIAwareness, knowledge, use, willingness to use and need of Pre-Exposure Prophylaxis (PrEP) during World Gay Pride 2017
Iniesta C, Álvarez-Del Arco D, García-Sousa LM, Alejos B, Díaz A, Sanz N, Garrido J, Meulbroek M, Pujol F, Moreno S, Fuster-Ruiz de Apocada MJ, Coll P, Antela A, Del Romero J, Ayerdi O, Riera M, Hernández J, Del Amo J. Awareness, knowledge, use, willingness to use and need of Pre-Exposure Prophylaxis (PrEP) during World Gay Pride 2017. Plos One. 2018; 13(10):e0204738
PUBMED DOITrends in new HIV diagnoses and factors contributing to late diagnosis among migrant populations in EU/EEA countries, 2014 to 2023.
Reyes-Urueña J, Stoppa G, Pizzolato F, van der Werf MJ, Deogan C, Cabral-Veríssimo V, Cortes-Martins H, Deblonde J, Diaz A, Hernando V, Milunka-Kojic E, Mossong J, O’Donnell K, Op de Coul E, Tsiara C, van Leest L, Van Beckhoven D, Wessman M, Whittaker R, the EU/EEA HIV network. Euro Surveill. 2024; 29(48): pii=2400759.
PUBMED DOICaracterísticas epidemiológicas de los brotes de hepatitis A en España (años 2015-2019)
13. Guerrero-Vadillo M, Peñuelas Martínez M, Varela Martínez C. Características epidemiológicas de los brotes de hepatitis A en España (años 2015-2019). BES [Internet]. 24 de enero de 2022 ;29(2). Disponible en: //revista.isciii.es/index.php/bes/article/view/1124
PUBMED DOIMarkers of inflammation and immune dysfunction and non-AIDS cancer risk in adults with HIV. v
Izquierdo R, Vallejo A, Suárez-García I, Martín-Hondarza A, Gutierrez F, Perez-Molina JA, García DV, Macías J, Rivero A, Olalla J, Montero-Alonso M, Asensi V, Moreno S, Jarrín I, Rava M; CoRIS cohort. J Acquir Immune Defic Syndr. 2025 Apr 7.
PUBMED DOICOVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA.1/BA.2 lineages among adults and adolescents in a multicentre primary care study, Europe, December 2021 to June 2022.
Lanièce Delaunay C, Martínez-Baz I, Sève N, Domegan L, Mazagatos C, Buda S, et al. Euro Surveill Bull Eur Sur Mal Transm Eur Commun Dis Bull. 2024 Mar;29(13).
PUBMED DOITrends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009
Diez M, Bleda MJ, Varela JR, Ordoñana J, Azpiri MA, Vall M, Santos C, Viloria L, de Armas C, Urena JM, Trullen J, Pueyo I, Martinez B, Puerta T, Vera M, Sanz I, Junquera ML, Landa MC, Martinez E, Camara MM, Belda J, Bru FJ, Diaz A; EPI-VIH Study Group. Trends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009. Euro Surveill. 2014;19 (47):20971.
PUBMED DOIValidation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q).
Weintraub D, Chaudhuri KR, Schrag A, Martinez-Martin P, Rizos A, Mamikonyan E, Gallagher J, Schoen I, Staunton J, Fernandes MP, Rodriguez-Blazquez C. Validation of the International Parkinson and Movement Disorder Society Non-Motor Symptoms Questionnaire (MDS-NMS-Q). Mov Disord. 2025 Jun;40(6):1037-1046.
PUBMED DOIExploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence.
Ojeda Sánchez C, García-Pérez J, Gómez-Barroso D, Domínguez-Castillo A, Pardo Romaguera E, Cañete A, Ortega-García JA, Ramis R. Exploring Urban Green Spaces' Effect against Traffic Exposure on Childhood Leukaemia Incidence. Int J Environ Res Public Health. 2023 Jan 31;20(3):2506.
PUBMED DOIMulticohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach
Domingo-Relloso A, Riffo-Campos AL, Zhao N, Ayala G, Haack K, Manterola C, Rhoades DA, Umans JG, Fallin MD, Herreros-Martinez M, Pollan M, Boerwinkle E, Platz EA, Jones MR, Bressler J, Joehanes R, Ryan CP, Gonzalez JR, Levy D, Belsky DW, Cole SA, Michaud DS, Navas-Acien A, Tellez-Plaza M. Multicohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach. JACC CardioOncol. 2024 Sep 10;6(5):731-742.
PUBMED DOICoordinated public health actions following the identification of a measles case arriving on an international flight, Spain: December 2022-January 2023.
López-Perea N et al. Travel Med Infect Dis, 2024.
DOIHow patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study.
Romay-Barja M, Pascual-Carrasco M, De Tena-Dávila MJ, Falcón M, Rodriguez-Blazquez C, Forjaz MJ, Ayala A, Molina-de la Fuente I, Burgos A, Muñoz A, Benito A. How patients with COVID-19 managed the disease at home during the first wave in Spain: a cross-sectional study. BMJ Open. 2021 May 20;11(5):e048702.
PUBMED DOIImpact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders.
López-Cuadrado T, Ortiz C, Ayuso-Álvarez A, Galán I. Impact of psychological distress on mortality in Spain. The importance of early detection and treatment of mental disorders. J Psychiatr Res. 2024 Jan;169:292-297.
PUBMED DOIGonorrhoea diagnoses in a network of STI clinics in Spain during the period 2006-2010: differences by sex and transmission route
Diaz A, Garriga C, Varela JA, Fernández E, Sanz I, Boronat J, Gual F, Colomo C, López de Munain J, Esteban V, Junquera ML, Martínez B, Pueyo I, Suárez J, Barberá MJ, Arando M, Ureña JM, Diez M; STI Study Group. Gonorrhoea diagnoses in a network of STI clinics in Spain during the period 2006-2010: differences by sex and transmission route. BMC Public Health. 2013;13:1093
PUBMED DOIBrotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020
11. Chong A, Peñuelas M, Guerrero M, Cabezas C, Díaz O, Martín C, et al. Brotes de transmisión alimentaria. Red Nacional de Vigilancia Epidemiológica. 2012-2020. BES [Internet]. 29 de marzo de 2022;29(5):53-6. Disponible en: //revista.isciii.es/index.php/bes/article/view/1157
PUBMED DOIEffectiveness and tolerability of dolutegravir/lamivudine in virologically suppressed people with HIV at 96 weeks in a multicentre cohort.
Suárez-García I, Alejos B, Moreno C, de Miguel R, Aldámiz-Echevarría T, García-Fraile LJ, Tasias Pitarch M, Pérez Martinez D, Antela A, Moreno S, Jarrín I; CoRIS cohort. HIV Med. 2025 Dec 31.
PUBMED DOIEstimating the number of people living with HIV and the undiagnosed fraction in Spain in 2013
Nuñez O, Hernando V, Diaz A. Estimating the number of people living with HIV and the undiagnosed fraction in Spain in 2013. AIDS. 2018; 32(17):2573-2581. doi: 10.1097/QAD.0000000000001989. FI (2017): 4,914. Q1.
PUBMED DOIRasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study.
Forjaz, M.J., Ayala, A., Schutte, L., Wissing MP, Temane QM, Campbell TCH, Carroll MTC. Rasch and Confirmatory Factor Analysis of the Community Wellbeing Index: A Multicountry Validation Study. Soc Indic Res 179, 47–66 (2025).
DOICardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin.
Sagastume D, Siero I, Mertens E, Peñalvo JL. Cardiometabolic Profile and Outcomes in Migrant Populations: A Review of Comparative Evidence from Migrants in Europe in Relation to Their Country of Origin. Curr Cardiol Rep. 2022 Dec;24(12):1799-1810.
PUBMED DOIInvestigating Local Patterns of Mumps Virus Circulation, Using a Combination of Molecular Tools
Gavilán AM, Perán-Ramos P, Sanz JC, García-Comas L, Pérez-Abeledo M, Castellanos AM, Berciano JM, López-Perea N, Masa-Calles J, Echevarría JE, Fernández-García A. Viruses. 2023 Dec 13;15(12):2420.
PUBMED DOIKey Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment.
Romay-Barja M, Iglesias-Rus L, Boquete T, Benito A, Blasco-Hernández T. Key Chagas disease missing knowledge among at-risk population in Spain affecting diagnosis and treatment. Infect Dis Poverty. 2021 Apr 23;10(1):55.
PUBMED DOIClinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study
López-Cuadrado T, Szmulewicz A, Öngür D, Martínez-Alés G. Clinical characteristics and outcomes of people with severe mental disorders hospitalized due to COVID-19: A nationwide population-based study. Gen Hosp Psychiatry. 2023 Sep-Oct;84:234-240.
PUBMED DOISeverity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014
14. Severi E, Georgalis L, Pijnacker R, Veneti L, Turiac IA, Chiesa F, Rizzo C, Martinelli D, Vold L, Herrador BG, Martinez CV, Sanchez EVM, Semenza JC, Lopalco P, Dahlström LA, Giesecke J. Severity of the clinical presentation of hepatitis A in five European countries from 1995 to 2014. International Journal of Infectious Diseases 2022; 118, 34-43
PUBMED DOIDiagnosis of HIV infection during pregnancy: Trends from a national cohort in Spain.
Suárez-García I, Alejos B, Moreno C, Izquierdo R, de la Cámara SP, Resa-Infante P, Merino VS, García-Arriaza J, Cabello-Úbeda A, Pérez-Martínez L, Palacios R, Hernando V, Jarrín I; CoRIS cohort. HIV Med. 2025 Nov 21.
PUBMED DOI